Protein Alignment Cyp4ad1 and cyp-25A3

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001040850.1
• Gene: cyp-25A3 / 4363046
• WormBaseID: WBGene00014697
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 123/524 - (23%)
• Similarity: 206/524 - (39%)
• Gaps: 108/524 - (20%)

  Fly    35 IPGPTPYPFVGNLFQFGLKPAEYPKKVLQYCRKYDF---------QGFRSLVFLQYHMMLSDPAE 90
            :.||.|:..:|||.|...:.|:     |.|...||:         :.|......|.::.:::..:
 Worm    36 LSGPEPHWLMGNLKQIIERKAK-----LGYDDSYDWYNKLHKQFGETFGIYFGTQLNINITNEED 95

  Fly    91 IQNILSSSSLLYKEHLYSFLRPWLGDGLLTSS------GARWLKHQKLYAPAFERSAIEGYLRVV 149
            |:.:...:...:.:....   |.:.|..|..|      .:.|...:...||.|....::.....:
 Worm    96 IKEVFIKNFSNFSDRTPP---PIIEDNKLKESLLQNTYESGWKHTRSAIAPIFSTGKMKAMHETI 157

  Fly   150 HRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDV- 213
            |.....|::.|...:.:.:.:|..:.....|||::.:.|...||:           ..:|..||
 Worm   158 HSKVDLFLEILKEKASSGQKWDIYDDFQGLTLDVIGKCAFAIDSN-----------CQRDRNDVF 211

  Fly   214 -VQERTF-------------------SIVKRFDALFRLTSYYMKQRRALSLLRSE------LNRI 252
             |..|.|                   .:.|.:..|:|.|          .|.::|      |..:
 Worm   212 YVNARKFITNIDIRHSKIISTSFLFPELSKLWKVLYRFT----------DLAKAEIPLVEGLADV 266

  Fly   253 ISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLD-GKVLKEREIIEEVSTFIFTGHDPIAAAISF 316
            ..:||....:::.         ..|.:||..:.| .|.:.::|:||....|:..|::..:.|:::
 Worm   267 YERRRGGEGSDSV---------DLLKLLLNREDDKSKPMTKQEVIENCFAFLLAGYETTSTAMTY 322

  Fly   317 TLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNR- 380
            ..|.||::..:|||..||   |......|......:..|.||:.:.:||||.||  |:|..:||
 Worm   323 CSYLLSKYPNVQQKLYEE---IMEAKENGGLTYDSIHNMKYLDYVYKETLRCYP--PVIHFSNRR 382

  Fly   381 --NPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPR 443
              ..|.|.|....|...|:.....:..|.:.:|.|..|.||||||  ......:.|.:||..|||
 Worm   383 CLKDITIRGQFYPKGAIVVCLPHTVHRNPENWDSPEEFHPERFEN--WEEKSSSLKWIPFGVGPR 445

  Fly   444 RCIAEKFAMYQMKALLSQLLRRFEILP---AVDGLPPGINDHSREDC--VPQSEYDPVLNIRVTL 503
            .|:..:||..:.|..:::||..||:..   ..|.:|         ||  |.....|||   |:.|
 Worm   446 YCVGMRFAEMEFKTTIAKLLDTFELKQFEGEADLIP---------DCNGVIMRPKDPV---RLHL 498

  Fly   504 KSEN 507
            |..|
 Worm   499 KPRN 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	111/477 (23%)
cyp-25A3	NP_001040850.1	CYP3A-like	73..495	CDD:410678	107/473 (23%)