DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4ad1 and Cyp313b1

DIOPT Version :9

Sequence 1:	NP_610380.1	Gene:	Cyp4ad1 / 35821	FlyBaseID:	FBgn0033292	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	461	Identity:	112/461 - (24%)
Similarity:	211/461 - (45%)	Gaps:	51/461 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 GPTPYPFVGNLFQFGLKPAEYPKKVLQYCRKYDFQ---GFRSLVFLQYHMMLSDPAEIQNILSSS 98
            ||..:|.:|    .||:... |:..|||......|   .|.|.:.....:.::||..::.||:|:
  Fly    34 GPIGWPLIG----MGLQMMN-PETFLQYMDGLSRQFKAPFISWMGTSCFLYINDPHSVEQILNST 93

  Fly    99 SLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVL 163
            ....|...|.|:...:||||.|||..||.||::|..|||.|..:..:|.:.:......:|||: |
  Fly    94 HCTNKGDFYRFMSSAIGDGLFTSSSPRWHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLE-L 157

  Fly   164 SDTQ-----EVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVK 223
            ...|     |::   :::.|..|:..|:...|:..:..:..:..:..|...|.:|..:|..|...
  Fly   158 EGVQHGKRLEIY---QILKKIVLEAACQTTMGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLSPWL 219

  Fly   224 RFDALFRLTSYYMKQRRALSLLRSELNRIISQRRHQLAA-ENTCQQGQPI-----NKPFLDVLLT 282
            ..|.::|.:..:..|::.:.:|...:.:::......:|| .|..||...:     :|......:.
  Fly   220 YPDLIYRRSGLFRLQQKVVGILFGFIEQLLEPIVSVVAANSNPDQQRSEMEMRGKSKAIFIEQVR 284

  Fly   283 AKLDGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEA 347
            ..::...|..:::.:|.:..|....:..:.|:.||:..|:.|...|:|..:|  .:.....:|:.
  Fly   285 EHVERGQLSWQDVRDEANVTIAATFETTSTALYFTILCLAMHPCYQEKLHKE--LVTELPPSGDI 347

  Fly   348 DLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDI----------NGTKVAKCTTVIMCLIA 402
            :|.:|.::.|.|::|.|.:||:..||::.|:....|.:          .||::.      :.:..
  Fly   348 NLEQLQRLEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIG------IDIYN 406

  Fly   403 MGYNEKYFDDPCTFRPERFENPTGNVGIE-----AFKSVPFSAGPRRCIAEKFAMYQMKALLSQL 462
            |..:|:.: .|.:    |..||..:.|::     ||..|||:.|.|.||..::|...||.||:::
  Fly   407 MQRDERVW-GPLS----RTYNPDAHFGLDSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARI 466

  Fly   463 LRRFEI 468
            .|.:.|
  Fly   467 FRSYRI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	112/461 (24%)
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	112/461 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	5	4.970