Protein Alignment Cyp4ad1 and CYP4F3

DIOPT Version :9

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 135/438 - (30%)
• Similarity: 229/438 - (52%)
• Gaps: 37/438 - (8%)

  Fly    88 PAEIQNIL-SSSSLLYKEHL-YSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAIEGYLRVVH 150
            |..|:.:| :.::::.|:.: ||||:||||||||.|:|.:|.:|:::..|||..:.::.|:::.:
Human   104 PTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFN 168

  Fly   151 RTGGQFVQKLDVL-SDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVV 214
            .:......|..:| |:.....|..|.::..|||.: :.......|....:.|:...||.:|..:|
Human   169 ESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSL-QKCVFSFDSHCQEKPSEYIAAILELSALV 232

  Fly   215 QERTFSIVKRFDALFRLTSYYMKQRRALSLLRSELNRIISQRRHQLAAENTCQ--QGQPINK--P 275
            .:|...|:...|.|:.||....:.|||..|:....:.:|.:||..|.::....  |.:..:|  .
Human   233 TKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLD 297

  Fly   276 FLDVLLTAK-LDGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIF 339
            |:||||.:| .|||.|.:.:|..|..||:|.|||..|:.:|:.||.|::|.|.|::..:|.:.:.
Human   298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL 362

  Fly   340 GENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDI-NGTKVAKCTTVIMCLIAM 403
            .:....|.:...|.|:.:|.:.|:|:|||:|.||.::|.....|.: :|..:.|   .|:|||::
Human   363 KDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPK---GIICLISV 424

  Fly   404 ---GYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRR 465
               .:|...:.||..:.|.||: |...........:|||||||.||.:.|||.:||.:|...|.|
Human   425 FGTHHNPAVWPDPEVYDPFRFD-PKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLR 488

  Fly   466 FEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENGIQIRL 513
            |.:||          ||:          :|.....:.|::|.|:.:|:
Human   489 FRVLP----------DHT----------EPRRKPELVLRAEGGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	126/393 (32%)
CYP4F3	NP_000887.2	p450	52..515	CDD:365848	134/435 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154788
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.650