Protein Alignment Cyp4ad1 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_956773.1
• Gene: cyp46a1.4 / 393451
• ZFINID: ZDB-GENE-040426-1224
• Length: 444
• Species: Danio rerio
• Alignment Length: 469
• Identity: 120/469 - (25%)
• Similarity: 207/469 - (44%)
• Gaps: 54/469 - (11%)

  Fly    62 LQYCRKY-DFQGFRSLVFLQYHMMLSDPAEIQNILSS-----SSLLYKEHLYSFLRPWLGDGLLT 120
            ||:..|| ......||.::.  :::..|...:.||.|     ...:|:.....|.:.:||.||:|
Zfish    13 LQWAEKYGPVYRINSLHYIA--IVVHCPEATKTILMSPKYTKDPFVYRRLFNLFGKRFLGYGLIT 75

  Fly   121 S-SGARWLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIV 184
            : ....|.:.:::..|||..|.:...:........:.:.||:.:::.:......:||...|||::
Zfish    76 AVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEEMANNKTPAVMHDLVNCVTLDVI 140

  Fly   185 CENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSYYMKQ-RRALSLLRSE 248
            |:.|.|.|.:.|..:.|....|: :||  :...|..:...|..||......:|| |.|..|||..
Zfish   141 CKVAFGVDLNFLTQKDSPFQNAV-ELC--LNGMTVDLRDPFFRLFPKNWKLIKQIRDAAELLRKT 202

  Fly   249 LNRIISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLKE---REIIEEVSTFIFTGHDPI 310
            ..:.|..|:  .|.:|    |:.:.|..|..:|.:..:..|...   .::::...||...|.:..
Zfish   203 GEKWIQNRK--TAVKN----GEDVPKDILTQILKSAEEENVNNTDDLEQMLDNFVTFFIAGQETT 261

  Fly   311 AAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLI 375
            |..:||.:..|.|:.||.::|..|...:.|..  .|.....|.:..||..:::|||||||:.|..
Zfish   262 ANQLSFAIMALGRNPEIYKRAKAEVDEVLGTK--REISNEDLGKFTYLSQVLKETLRLYPTAPGT 324

  Fly   376 ARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKS----V 436
            .|.....:.|:|.|:....:|:.........||:|.||..|.||||:       :.|.|.    .
Zfish   325 NRWLHEDMIIDGIKIPGGCSVMFSSYVSQRLEKFFKDPLKFDPERFD-------VNAPKPYYCYF 382

  Fly   437 PFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRV 501
            ||:.|||.|:.:.|:..:.|.:|::||:|||.                 ..||...:|  :....
Zfish   383 PFALGPRTCLGQVFSQMEAKVVLAKLLQRFEF-----------------SLVPGQSFD--IKDTG 428

  Fly   502 TLKSENGIQIRLRK 515
            ||:.::|:...:::
Zfish   429 TLRPKSGVICNIKQ 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	116/451 (26%)
cyp46a1.4	NP_956773.1	CYP46A1-like	9..438	CDD:410706	120/463 (26%)