Protein Alignment Cyp4ad1 and Cyp49a1

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_610588.2
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 121/520 - (23%)
• Similarity: 222/520 - (42%)
• Gaps: 81/520 - (15%)

  Fly    35 IPGPTPYPFVGNLFQFG-----LKPAEYPKKVLQYCRKY-------DFQGFRSLVFLQYHMMLSD 87
            :|||.|.|.:||.::|.     .|.::..|.:.:....|       ...|...|:|      :.|
  Fly   103 VPGPYPLPLIGNSWRFAPLIGTYKISDLDKVMNELHVNYGKMAKVGGLIGHPDLLF------VFD 161

  Fly    88 PAEIQNILSSSSLLYKEHLYSFLRPWLGD----------GLLTSSGARW-LKHQKLYAPAFERSA 141
            ..||:||......:........||.:.||          ||:...|.:| ...|::.....:...
  Fly   162 GDEIRNIFKKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWEAFRQEVQHILLQPQT 226

  Fly   142 IEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQ----------ELVAKCTLD--IVCENATGQDSS 194
            .:.|:..::....:|:.:::::.|.::...|.          |.|.:.:||  :.|.:..|.:
  Fly   227 AKKYIPPLNDIASEFMGRIELMRDEKDELPANFLHELYKWALESVGRVSLDTRLGCLSPEGSE-- 289

  Fly   195 SLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRL--TSYYMKQRRALSLLRSELNRIISQRR 257
                |...:..||......|.|....:     .|:|:  |..|....:||....:...:.|.:..
  Fly   290 ----EAQQIIEAINTFFWAVPELELRM-----PLWRIYPTKAYRSFVKALDQFTAICMKNIGKTM 345

  Fly   258 HQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIF-TGHDPIAAAISFTLYTL 321
            .:..|:    :.:.::|...|:.:..::..|. ..|::...::..:| .|.|..:.|.|.|:|.|
  Fly   346 DKADAD----EARGLSKSEADISIVERIVRKT-GNRKLAAILALDLFLVGVDTTSVAASSTIYQL 405

  Fly   322 SRHSEIQQKAAEEQRRIFGENFAGEADLAR--LDQMHYLELIIRETLRLYPSVPLIARTNRNPID 384
            :::.:.|:|..:|.:::|...   |||:.:  |:||.||...::||||:.|.|....|:.::...
  Fly   406 AKNPDKQKKLFDELQKVFPHR---EADINQNVLEQMPYLRACVKETLRMRPVVIANGRSLQSDAV 467

  Fly   385 INGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFEN--------PTGNVGIEAFKSVPFSAG 441
            |||..|.|.|.||...:.:..:..||.:|..|.|||:..        |..|..|..|.|:||..|
  Fly   468 INGYHVPKGTHVIFPHLVVSNDPAYFPEPKRFLPERWLKQSTDAAGCPHANQKIHPFVSLPFGFG 532

  Fly   442 PRRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSE 506
            .|.|:..:||..::..||:::.|::::..........:|    ...:|||.    ||.::||:.|
  Fly   533 RRMCVGRRFAEIELHTLLAKIFRKYKVSYNSGEFVYRVN----STYIPQSP----LNFKLTLRDE 589

  Fly   507  506
              Fly   590  589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	109/470 (23%)
Cyp49a1	NP_610588.2	CYP24A1-like	138..581	CDD:410677	106/475 (22%)