Protein Alignment Cyp4ad1 and cyp3c1

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_997838.1
• Gene: cyp3c1 / 324340
• ZFINID: ZDB-GENE-030131-3060
• Length: 505
• Species: Danio rerio
• Alignment Length: 510
• Identity: 115/510 - (22%)
• Similarity: 211/510 - (41%)
• Gaps: 99/510 - (19%)

  Fly     6 IAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPFVGNLFQFGLKPAEYPKKVLQY---C-R 66
            :.:::.|:|:..||....:...:.     ||||.|.||||...       .|.|.:..:   | :
Zfish    13 LVVLVITLLLIYGVWPHGFFKKLG-----IPGPRPLPFVGTAL-------SYSKGICNFDIECSK 65

  Fly    67 KYD-----FQGFRSLVFLQYHMMLSDPAEIQNILSS---SSLLYKEHLYSFLRPWLGDGLLTSSG 123
            ||.     :.|...|      ::::|...|:.||..   |:...:.::...|.....||:.....
Zfish    66 KYGKVWGIYDGRLPL------LLVTDLEMIKTILVKDCYSTFTNRRNMNPDLVGPFADGITLVKD 124

  Fly   124 ARWLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENA 188
            .||.:.:...:|.|....::....:......:|::.:: ..|.......:::||..:||:|..::
Zfish   125 ERWRRIRSSLSPYFTSGRLKEIFPIAMTHADRFIKNME-KKDPNLPLKIKDVVAPYSLDVVASSS 188

  Fly   189 TGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRL---------------------- 231
            ...|..|:|........:||         :|..:.....||.|
Zfish   189 FSVDFDSINNPDDPFVTSIK---------SFFNINPLSPLFLLLAFCPSAANLLAKMGISVFSRS 244

  Fly   232 -TSYYMKQRRALSLLRSELNR----------IISQRRHQLAAENTCQQGQPINKPFLDVLLTAKL 285
             |.:|.|   ||..::.|.|.          :|..:......::|..: ||:
Zfish   245 TTDFYYK---ALRKIKDEHNESNGRVDFLKLMIQNQIPDDQVKDTASE-QPV------------- 292

  Fly   286 DGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLA 350
              |.|.:.||:.:...||..|::..:..:|:.||.|:.:.:..:|..||    ..:||..:..:.
Zfish   293 --KGLTDHEILSQSFIFILGGYETTSTTLSYLLYNLATNPDCLEKLVEE----IDKNFPLDIPIT 351

  Fly   351 --RLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDP 413
              .|.:|.|||:.|.|::|::|:.|.:.|..:..::|||..:.|.|.|.:.|..:..:...::.|
Zfish   352 YDALMRMDYLEMAIHESMRVFPAGPRLERVCKKTVEINGITIPKNTLVGIPLYVLSRDPDLWESP 416

  Fly   414 CTFRPERFENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEI 468
            ..|:|||| :|.....|.....:||..|||.||..:||:..||.|:.:||:::.:
Zfish   417 NEFKPERF-SPESKTEINQCAFMPFGLGPRNCIGMRFALMMMKLLVVKLLQKYTV 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	96/434 (22%)
cyp3c1	NP_997838.1	cytochrome_P450	66..495	CDD:477761	99/445 (22%)