Protein Alignment Cyp4ad1 and Cyp4f39

DIOPT Version :9

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_796281.1
• Gene: Cyp4f39 / 320997
• MGIID: 2445210
• Length: 532
• Species: Mus musculus
• Alignment Length: 556
• Identity: 145/556 - (26%)
• Similarity: 257/556 - (46%)
• Gaps: 94/556 - (16%)

  Fly     1 MFLIAIAIILATILVFK-GVRIFN-YIDHMAGIMEMIPGPTP---YPFVGNLFQF--GLKPAEYP 58
            :::::..::|.....|: .||.|. :.|......::...|.|   :..:|::..:  ..|..:..
Mouse    21 VYVVSALLLLVLFFFFRLLVRAFKLFSDFRITCRKLSCFPEPPGRHWLLGHMSMYLPNEKGLQNE 85

  Fly    59 KKVLQYCRKYDFQGFRSLVFLQYHMMLS------------DPAEIQNILSSSSLL--YKEHLYSF 109
            ||||.               ..:|::|:            .|..|:.:|.:|:.:  ..|..|||
Mouse    86 KKVLD---------------TMHHIILAWVGPFLPLLVLVHPDYIKPVLGASAAIAPKDEFFYSF 135

  Fly   110 LRPWLGDGLLTSSGARWLKHQKLYAPAFERSAIEGYLR-------VVHRTGGQFVQKLDVLSDTQ 167
            |:||||||||.|.|.:|.:|::|..|||....::.|::       ::|....:.:.:..|.|
Mouse   136 LKPWLGDGLLISKGNKWSRHRRLLTPAFHFDILKPYMKIFNQCTNIMHAKWRRHLAEGSVTS--- 197

  Fly   168 EVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLT 232
              ||..|.::..|||.: :......:|......||...:|.:|..:|..|.:.:....|.::.||
Mouse   198 --FDMFEHISLMTLDSL-QKCVFSYNSDCQERMSDYISSIIELSALVVRRQYRLHHYLDFMYYLT 259

  Fly   233 SYYMKQRRALSLLRSELNRIISQRRHQLAAENT-----CQQGQPINKPFLDVLLTAK-LDGKVLK 291
            :...:.|:|...:.:....:|.:||..|..:..     .:||:.::  |:||||.|| .:||.|.
Mouse   260 ADGRRFRQACDTVHNFTTEVIQERRQALRQQGAEAWLKAKQGKTLD--FIDVLLLAKDEEGKELS 322

  Fly   292 EREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMH 356
            :.:|..|..||:|.|||..::.:|:.|:.|:::.|.|:|..||.:.:.......|.|...|.|:.
Mouse   323 DEDIRAEADTFMFEGHDTTSSGLSWALFNLAKYPEYQEKCREEIQEVMKGRELEELDWDDLTQLP 387

  Fly   357 YLELIIRETLRLYPSVPLIARTNRNPIDI-NGTKVAKCTTVIMCLIAM---GYNEKYFDDPCTFR 417
            :..:.|:|:||.:|.|.||:|.....|.: :|..:.|   .|:||:::   .:|...:.|...:.
Mouse   388 FTTMCIKESLRQFPPVTLISRRCTEDIKLPDGRVIPK---GIICLVSIYGTHHNPIVWPDSKVYN 449

  Fly   418 PERFENPTGNVGIE-AFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGIND 481
            |.||:..|...... ||  ||||||||.||.:.|||.:|:.:::..|.||.:
Mouse   450 PYRFDPDTPQQRSPLAF--VPFSAGPRNCIGQSFAMAEMRVVVALTLLRFRL------------- 499

  Fly   482 HSREDCVPQSEYDPVLNIR----VTLKSENGIQIRL 513
                      ..|....:|    :.|::|||:.:.:
Mouse   500 ----------SVDRTHKVRRKPELILRTENGLWLNV 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	133/470 (28%)
Cyp4f39	NP_796281.1	p450	60..515	CDD:365848	135/505 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.650