Protein Alignment Cyp4ad1 and Cyp4f4

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_775146.1
• Gene: Cyp4f4 / 286904
• RGDID: 708363
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 153/525 - (29%)
• Similarity: 261/525 - (49%)
• Gaps: 42/525 - (8%)

  Fly     1 MFLIAIAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYP-FVGNLFQFGLKPAEYP-KKVLQ 63
            :.||..:.:|..:|....: .:....|:..    .|.|..:. |:|:|..  :.|.|.. |:|.:
  Rat    22 LLLIGASWLLVRVLTQTYI-FYRTYQHLCD----FPQPPKWNWFLGHLGM--ITPTEQGLKQVTK 79

  Fly    64 YCRKYDFQGFRS-LVFLQYHMMLSDPAEIQNILS-SSSLLYKEHL-YSFLRPWLGDGLLTSSGAR 125
            ....|. |||.: |..:...:.|..|..|:::|| |:|:..||.: ||||:||||||||.|.|.:
  Rat    80 LVATYP-QGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFLKPWLGDGLLLSDGDK 143

  Fly   126 WLKHQKLYAPAFERSAIEGYLRVVH-RTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENAT 189
            |..|:::..|||..:.::.|:::.: .|.....:..|:.|......|..:.::..|||.: :...
  Rat   144 WSCHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQDLASGGSARLDMFKNISLMTLDSL-QKCV 207

  Fly   190 GQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSYYMKQRRALSLLRSELNRIIS 254
            ....|:...:.|:...||.:|..:|.:|...::...|:|::||....:..:|..|:.:..:.:|.
  Rat   208 FSFDSNCQEKPSEYISAILELSALVAKRYQQLLLHTDSLYQLTHNGRRFHKACKLVHNFTDAVIQ 272

  Fly   255 QRRHQLAA--ENTCQQGQPINK--PFLDVLLTAK-LDGKVLKEREIIEEVSTFIFTGHDPIAAAI 314
            .||..|.:  |:...:.:..:|  .|:||||..| .|||.|.:.:|..|..||:|.|||..|:.:
  Rat   273 GRRRALPSQHEDDILKAKARSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMFEGHDTTASGL 337

  Fly   315 SFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTN 379
            |:.||.|:||.|.|::..:|.|.:..:..:.|.:...|.|:.:|.:.|:|:|||:|.|.:|:|..
  Rat   338 SWILYNLARHPEYQERCRQEVRELLRDRESTEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRRC 402

  Fly   380 RNPIDI-NGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPR 443
            ...|.: :|..:.|....|:.:.|..:|...:.||..:.|.||: |...........:|||||||
  Rat   403 TQDIVLPDGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRFD-PENIKDRSPLAFIPFSAGPR 466

  Fly   444 RCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENG 508
            .||.:.|||.:||..|:..|.||.:||                    .:.:|.....:.|::|.|
  Rat   467 NCIGQTFAMNEMKVALALTLLRFRVLP--------------------DDKEPRRKPELILRAEGG 511

  Fly   509 IQIRL 513
            :.:|:
  Rat   512 LWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	135/447 (30%)
Cyp4f4	NP_775146.1	CYP4F	74..515	CDD:410772	140/463 (30%)