Protein Alignment Cyp4ad1 and erg11

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_592990.1
• Gene: erg11 / 2542599
• PomBaseID: SPAC13A11.02C
• Length: 495
• Species: Schizosaccharomyces pombe
• Alignment Length: 497
• Identity: 123/497 - (24%)
• Similarity: 190/497 - (38%)
• Gaps: 112/497 - (22%)

  Fly    42 PFVGNLFQFGLKPAEYPKKVLQYCR-KYD--------------FQGFRSLVFLQYHMMLSDPAEI 91
            ||||:...:|:.|..:    .:.|| ||.              |.|.:...|| ::..|:|
pombe    41 PFVGSAVAYGMDPYVF----FRECRAKYGDVFTFVCMGRKMTAFLGVQGNDFL-FNGKLAD---- 96

  Fly    92 QNILSSSSLLYKEHLYSFL-RPWLG-DGLLTSSGARWLKHQKLYAPAFERSAIEGYLRVVHRTGG 154
                     |..|..||.| .|..| |.:.......:::|:|........|....|:.::
pombe    97 ---------LNAEEAYSHLTTPVFGKDVVYDIPNHVFMEHKKFIKSGLGFSQFRSYVPLI----- 147

  Fly   155 QFVQKLDVLSDTQEVFD------AQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDV 213
              :.::|....|...|.      |..|.....:.|...:.|.|.:....|..:.......||
pombe   148 --LNEMDAFLSTSPDFGPGKEGVADLLKTMPVMTIYTASRTLQGAEVRKGFDAGFADLYHDL--- 207

  Fly   214 VQERTFSIVKRFDALFRLTSYYMKQR--RALSLLRSELNRIISQRRHQLAAENTCQQGQPINKPF 276
              ::.||.|   :.:|........:|  ||..:::....:||..||.  :.||          |.
pombe   208 --DQGFSPV---NFVFPWLPLPRNRRRDRAHKIMQKTYLKIIKDRRS--STEN----------PG 255

  Fly   277 LDV---LLTAKL-DGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRR 337
            .|:   |::.|. ||:.|||.||...:...:..|....||.|.:.|..|....||.:...|||:|
pombe   256 TDMIWTLMSCKYRDGRPLKEHEIAGMMIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWEEQKR 320

  Fly   338 IFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDINGTKVAKCTTVI----M 398
            :.|||.  |....:...|..|..:|:|||||:|.:....|..:..:.:.|:|:     ||    .
pombe   321 VVGENL--ELKFDQYKDMPLLNYVIQETLRLHPPIHSHMRKVKRDLPVPGSKI-----VIPANNY 378

  Fly   399 CLIAMGY---NEKYFDDPCTFRPERFE---NPTGNV-------GI----EAFKSVPFSAGPRRCI 446
            .|.|.|.   .|:||.....|.|:|:.   |...|.       |:    .|...:||.||..|||
pombe   379 LLAAPGLTATEEEYFTHATDFDPKRWNDRVNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCI 443

  Fly   447 AEKFAMYQMKALLSQLLRRFE-----ILPAVD-----GLPPG 478
            .|:||...:..::|:.:..:.     .:|.||     .||.|
pombe   444 GEQFAYMHLSTIISKFVHDYTWTLIGKVPNVDYSSMVALPLG 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	111/451 (25%)
erg11	NP_592990.1	CYP51-like	60..492	CDD:410668	117/474 (25%)