Protein Alignment Cyp4ad1 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 582
• Identity: 118/582 - (20%)
• Similarity: 219/582 - (37%)
• Gaps: 135/582 - (23%)

  Fly     4 IAIAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPFVGNL--FQFGL--KPAEYPKKVLQY 64
            :.::::|..:|.:.....|:.:..:.     |..|.|.||||||  |:.|.  ...|..::....
  Rat    18 VTLSVVLLALLKWYSTSAFSRLRKLG-----IRHPEPSPFVGNLMFFRQGFWESHLELRERYGPL 77

  Fly    65 CRKYDFQGFRSLVFLQYHMMLSDPAEIQNILSSSSLLYKEHLYSFLRPWL-GDGLLTSSGARWLK 128
            |..|        :..:.::::|||..|:.:|..:...:...:.|.|.|.| .|.:|.....||.:
  Rat    78 CGYY--------LGRRMYIVISDPDMIKEVLVENFSNFSNRMASGLEPKLIADSVLMLRDRRWEE 134

  Fly   129 HQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDS 193
            .:.....||....:.....::.:.....:..|...:.:.:.||.|......|.::|...|.|.:.
  Rat   135 VRGALMSAFSPEKLNEMTPLISQACELLLSHLKHSAASGDAFDIQRCYCCFTTNVVASVAFGIEV 199

  Fly   194 SSLNGETSDLHGAIKDLCDVVQ--ERTFSIVKRFDALFRLTSYYMKQRRALSLL----------- 245
            :|.:......          ||  :|.|:              :...|..|:|:
  Rat   200 NSQDAPEDPF----------VQHCQRVFA--------------FSTPRPLLALILSFPSIMVPLA 240

  Fly   246 -------RSELN--------RIISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLD--------- 286
                   |.|||        .:|:.|..|.|.|   ::|.     ||.::|.|:..
  Rat   241 RILPNKNRDELNGFFNTLIRNVIALRDKQTAEE---RRGD-----FLQMVLDAQRSMSSVGVEAF 297

  Fly   287 -------------------------GKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSE 326
                                     .|.|...||..:...|:..||:.....:||..|.|:.|.|
  Rat   298 DMVTEALSSAECMGDPPQRCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPE 362

  Fly   327 IQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDINGTKVA 391
            .|::..:|. .:|.|...........:.:.||::::.||||:||......|......::.|..:.
  Rat   363 CQERLLKEV-DLFMEKHPAPEYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCEVLGQHIP 426

  Fly   392 KCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIE--AFKSVPFSAGPRRCIAEKFAMYQ 454
            ..:.:.:.:.|:.::.:::.:|.||.||||   |....::  .|..:||.||||.|:..:..:..
  Rat   427 AGSVLEIAVGALHHDPEHWPNPETFDPERF---TAEARLQQKPFTYLPFGAGPRSCLGVRLGLLV 488

  Fly   455 MKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENGIQIRLRKR 516
            :|..|.|:|.:|                 |.:..|:::....|..:..|..:||:.:::..|
  Rat   489 VKLTLLQVLHKF-----------------RFEACPETQVPLQLESKSALCPKNGVYVKIVSR 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	100/502 (20%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	102/513 (20%)