Protein Alignment Cyp4ad1 and Cyp4f17

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001094915.1
• Gene: Cyp4f17 / 208285
• MGIID: 3646233
• Length: 524
• Species: Mus musculus
• Alignment Length: 541
• Identity: 151/541 - (27%)
• Similarity: 251/541 - (46%)
• Gaps: 112/541 - (20%)

  Fly    51 GLKP-AEYPKKVLQ---------------------YCR---------KYDFQGFRSLV------- 77
            ||.| |.:|.::||                     |||         ::.|.|..|:|
Mouse    10 GLGPGAAFPWQLLQLVGASLFLARILTWICAFYDNYCRLRCFPEPPSRHWFWGHMSMVKNNEEGL 74

  Fly    78 ------FLQYH-------------MMLSDPAEIQNILSSSSLLYKEHL--YSFLRPWLGDGLLTS 121
                  ..|:|             :.|..|..|..||.:|:.:..:.:  |.||:||||||||.|
Mouse    75 QLLTERSHQFHDVHLCWIGPFYPILRLIHPKFIGPILQASAAVAPKEMIFYGFLKPWLGDGLLVS 139

  Fly   122 SGARWLKHQKLYAPAFERSAIEGYLR-------VVHRTGGQFVQK----LDVLSDTQEVFDAQEL 175
            :|.:|.:|:.|..|||....::.|::       ::|....:...|    ||:|          |.
Mouse   140 AGEKWSRHRHLLTPAFHFDILKPYMKNFNKSVNIMHAKWQRLTTKGTACLDML----------EH 194

  Fly   176 VAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSYYMKQRR 240
            ::..|||.: :|......|:.....|:...||::|..::.:|........|.|:..|:...:.|:
Mouse   195 ISLMTLDSL-QNCVFSFDSNCQESPSEYIAAIQELSSLIVKRHHQPFLYLDFLYYCTADGRRFRK 258

  Fly   241 ALSLLRSELNRIISQRRHQLAAENTCQQGQPINK----PFLDVLLTAKLD-GKVLKEREIIEEVS 300
            |..|:.:..:.:|.:||..|:::|..:..:...|    .|:||||.||.: ||.|.:.:|..|..
Mouse   259 ACDLVHNFTDAVIRERRRTLSSQNLDEFLKSKTKSKTLDFIDVLLLAKDEHGKELSDEDIRAEAD 323

  Fly   301 TFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRET 365
            ||:|.|||..|:|:|:.||.|:||.|.|::..:|.:.:.......|.:...|.|:.:|.:.|:|:
Mouse   324 TFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQELLRGREPQEIEWDDLAQLPFLTMCIKES 388

  Fly   366 LRLYPSVPLIARTNRNPIDI-NGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERF--ENPTGN 427
            |||:|.|.:|:|.....:.: :|..:.|.|..::.:..:.:|.:.:.||..:.|.||  |||...
Mouse   389 LRLHPPVTVISRCCTQDVVLPDGRVIPKGTDCVISIFGVHHNPEVWPDPEVYDPFRFDPENPQKR 453

  Fly   428 VGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSE 492
            ..: ||  :|||||||.||.:.|||.:||..|:..|.||.:||                    .:
Mouse   454 SPL-AF--IPFSAGPRNCIGQTFAMREMKVALALTLLRFRVLP--------------------GD 495

  Fly   493 YDPVLNIRVTLKSENGIQIRL 513
            .:|.....:.|::|.|:.:|:
Mouse   496 KEPRRKPELILRAEGGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	138/484 (29%)
Cyp4f17	NP_001094915.1	CYP4F	74..515	CDD:410772	136/474 (29%)