Protein Alignment Cyp4ad1 and cyp-13A1

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001369869.1
• Gene: cyp-13A1 / 188361
• WormBaseID: WBGene00011677
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 489
• Identity: 115/489 - (23%)
• Similarity: 211/489 - (43%)
• Gaps: 91/489 - (18%)

  Fly    35 IPGPTPYPFVG-------NLFQFGLKPAEYPKKVLQYCRKYDF-QG-FRSLVFLQYHMMLSDPAE 90
            :.||..:|.:|       |.|.|.|:..|:.||   :.:.|.| :| .::||       :|||..
 Worm    32 VVGPMGFPVLGVFLNSLDNNFPFPLQCREWTKK---FGKIYGFTEGTLKTLV-------ISDPEL 86

  Fly    91 IQNILSSSSLLYKEHLYSFLR-PWLGD-------GLLTSSGARWLKHQKLYAPAFERSAIEGYLR 147
            :..:.    :...::.|...| |..||       .|..:.|.||.:.:.:.:|.|..|::....:
 Worm    87 VHEVF----VTQYDNFYGRKRNPIQGDSEKEKRTNLFAAQGFRWKRLRAISSPTFSNSSLRKLYQ 147

  Fly   148 VVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCD 212
            .|..:..:.::.::..|...:..|..:...:.|||::...|.||..|.:      ....|..:..
 Worm   148 TVEDSALELLRHIEKQSAGGKQIDMLKFYQEFTLDVIGRIAMGQTDSQM------FKNPIMPIVS 206

  Fly   213 VVQERTFSIVKRFDALFRLTSYYMKQRRALSLLRS-------ELNRI--------ISQRRHQLAA 262
            .:.:..|:.:.....:|  .::.::..|.: ||::       ::|.|        |.||...  .
 Worm   207 KLFQGNFAKLFLIGGIF--PTFLVEIIRQI-LLKNLKVGSFRKINEITLDAIHNRIKQREED--Q 266

  Fly   263 ENTCQQGQPINKPFLDVLLTAKLD-------------------GKVLKEREIIEEVSTFIFTGHD 308
            :|..:.|:|.:  |:|:.|.||.:                   .:.|...||:.:.:.|:..|.|
 Worm   267 KNGIEIGEPAD--FIDLFLDAKAEDVEHFGENNGDFSKSTTYTNRQLTTEEIVGQCTVFLIAGFD 329

  Fly   309 PIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVP 373
            ..|.::|:..|.|:.|.|||:|..||..|   |....|..:.:|.::.|:|.:.:|.||||| :.
 Worm   330 TTALSLSYATYLLATHPEIQKKLQEEVNR---ECPNPEVTIDQLSKLKYMECVFKEALRLYP-LG 390

  Fly   374 LIARTNRNPIDINGTKVAKCTTVIMCLIAMG----YNEK--YFDDPCTFRPERFENPTGNVGIEA 432
            ..|.:.|   .:..||:......:..:|.:.    :.:.  :.||...|:|||::.|..:...:.
 Worm   391 AFANSRR---CMRNTKLGNMKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQK 452

  Fly   433 FKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRF 466
            ...:||..|||:||..:.|..:.|.||..:||:|
 Worm   453 SGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKF 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	101/442 (23%)
cyp-13A1	NP_001369869.1	CYP3A-like	64..510	CDD:410678	105/457 (23%)