Protein Alignment Cyp4ad1 and cyp-13B1

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_510233.1
• Gene: cyp-13B1 / 181462
• WormBaseID: WBGene00008519
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 127/540 - (23%)
• Similarity: 217/540 - (40%)
• Gaps: 128/540 - (23%)

  Fly     3 LIAIAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPFVGNLFQFG--LKPAEYPKKVLQYC 65
            :|.:.::.|||..:     |.:| |.......|.||...||:||.:...  .||..|  .:.::.
 Worm     4 IIVLVVLFATIAGY-----FKWI-HTYWRRRGISGPEGLPFIGNYYDLADVNKPRGY--LIHKWT 60

  Fly    66 RKYDFQGFRSLVFLQYH-----MMLSDPAEIQNI-LSSSSLLY----KEHLYSFL-----RPWLG 115
            :|:      ..||..|.     :::||...:|.: |......|    ..|::..|     .|.:
 Worm    61 QKF------GKVFGYYEGAVPVLVVSDMDMLQELFLKKFDNFYARKSTNHIHGNLECSKSEPRI- 118

  Fly   116 DGLLTSSGARWLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAK-- 178
             .|.||.||||.:.:.|.:|.|...|    |:.||          ||:.|:  ..:..:|:||
 Worm   119 -NLFTSRGARWKRLRALASPGFSVKA----LKQVH----------DVMEDS--AINMVDLMAKHE 166

  Fly   179 -------------CTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQE---RTFSIVK-RFD 226
                         .|.|::...|.||.:|.|...:.         .::|:.   ||..::. .|.
 Worm   167 DGKPFNIHAYFQEFTYDVISRLAMGQPNSELFNNSG---------VEIVKSIFMRTHRVLPWYFT 222

  Fly   227 ALFRLTSYYMKQ-------------RRALSLLRSELNRIISQRRH--QLAAENTCQQGQPINKPF 276
            .||....:.:|:             .:.|.:.:..:...|.:|..  :|..||.       ...|
 Worm   223 VLFPQFEHLVKRMFYNHAAVQGGDIEKLLLICKKTVESRIQEREENAKLGFENA-------ENDF 280

  Fly   277 LDVLLT------------AKLDGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQ 329
            :|:.|.            :.::.||..| ::|.....|:..|.|..|.::::..|.|::|.|..:
 Worm   281 IDMFLNYYSEQVEDIEFGSTVEKKVTAE-DVIGACFVFLLAGFDTTANSLAYASYLLAKHPEKMK 344

  Fly   330 KAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYP------SVPLIARTNRNPIDINGT 388
            .|.||...:.|.......|:.:|   .||:.::||:|||||      |...:..|....|.|:
 Worm   345 LAQEEVDTVVGSENVSYDDMTKL---KYLDAVVRESLRLYPVAWFACSRECVKPTTLGDIYID-- 404

  Fly   389 KVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMY 453
            |..|....:|.|...  .|.:.::...|.|||:..|:..   .....:||.||||:|:..:..:.
 Worm   405 KGVKIEADVMSLHRS--KEIWGENADDFVPERWLEPSSR---HTMSWIPFGAGPRQCVGMRLGLS 464

  Fly   454 QMKALLSQLLRRFEILPAVD 473
            :.|..|:.||||::::..|:
 Worm   465 EAKTALAHLLRRYDLVAGVE 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	109/468 (23%)
cyp-13B1	NP_510233.1	CYP3A-like	62..500	CDD:410678	110/474 (23%)