Protein Alignment Cyp4ad1 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 493
• Identity: 126/493 - (25%)
• Similarity: 214/493 - (43%)
• Gaps: 74/493 - (15%)

  Fly    13 ILVFKGVRIFNYIDHMAGIMEM--IPGPTPYPFVGNLFQFGLKPAEYPKKVLQYCRK-------- 67
            :||...|.::.|..|..||.:.  ||||.|.||:|.:..:.....|:.|    ||.|
  Rat    14 LLVISLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTILAYRKGFWEFDK----YCHKKYGKLWGL 74

  Fly    68 YDFQGFRSLVFLQYHMMLSDPAEIQNILSSSSLLYKEHLYSFL--RPWLGDGLL-----TSSGAR 125
            ||.:        |..:.::||..|:.:      |.||...:|.  |.:...|:|     .|....
  Rat    75 YDGR--------QPVLAITDPDIIKTV------LVKECYSTFTNRRNFGPVGILKKAISISEDEE 125

  Fly   126 WLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATG 190
            |.:.:.|.:|.|....::....::::.....|:.:...|:..:....:::....::|::...:.|
  Rat   126 WKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFGAYSMDVITATSFG 190

  Fly   191 QDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSYY-------------MKQRRAL 242
            .:..|||.........||.|.      .|.|   ||.||...:.:             |..|..:
  Rat   191 VNVDSLNNPQDPFVEKIKKLL------KFDI---FDPLFLSVTLFPFLTPLFEALNVSMFPRDVI 246

  Fly   243 SLLRSELNRIISQRRHQLAAENTCQQGQPINKPFLDVLLTA-----KLDGKVLKEREIIEEVSTF 302
            ...::.:.|:         .||..::.:.....||.:::.:     |...|.|.:.||:.:...|
  Rat   247 DFFKTSVERM---------KENRMKEKEKQRMDFLQLMINSQNSKVKDSHKALSDVEIVAQSVIF 302

  Fly   303 IFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLR 367
            ||.|::..::|:||.||.|:.|.:||:|..:|........  ..|....|.||.||::::.||||
  Rat   303 IFAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALPNK--AHATYDTLLQMEYLDMVVNETLR 365

  Fly   368 LYPSVPLIARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEA 432
            |||....:.|..:..::|||..:.|.|.|::...|:..:..|:.:|..||||||.....: .|..
  Rat   366 LYPIAGRLERVCKTDVEINGVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQD-NINP 429

  Fly   433 FKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILP 470
            :..:||..|||.||..:||:..||..|.::|:.|...|
  Rat   430 YMYLPFGNGPRNCIGMRFALMNMKVALVRVLQNFSFQP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	104/423 (25%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	106/436 (24%)