Protein Alignment Cyp4ad1 and Cyp19a1

DIOPT Version :9

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001335100.1
• Gene: Cyp19a1 / 13075
• MGIID: 88587
• Length: 503
• Species: Mus musculus
• Alignment Length: 439
• Identity: 95/439 - (21%)
• Similarity: 175/439 - (39%)
• Gaps: 71/439 - (16%)

  Fly    95 LSSSSLLYKEHLYSFLRPWL-GDGLL----TSSGARWLKHQ------------------------ 130
            :.|:...|.:....|:|.|: |:..|    :||....:||.
Mouse    70 IGSACNYYNKMYGEFMRVWISGEETLIISKSSSMFHVMKHSHYISRFGSKRGLQCIGMHENGIIF 134

  Fly   131 -------KLYAPAFERSAI-EGYLRVVH---RTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIV 184
                   :...|.|.::.. .|.:|:|.   .:..|.:.:|..::||....|...|:....||
Mouse   135 NNNPSLWRTIRPFFMKALTGPGLVRMVEVCVESIKQHLDRLGEVTDTSGYVDVLTLMRHIMLD-- 197

  Fly   185 CENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSYYMKQRRALSLLRSEL 249
                  ..:....|...|....:|.:..........::|. :..|:::..|.|..|::..|:.|:
Mouse   198 ------TSNMLFLGIPLDESAIVKKIQGYFNAWQALLIKP-NIFFKISWLYRKYERSVKDLKDEI 255

  Fly   250 NRIISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIFTGHDPIAAAI 314
            ..::.::||:::.....:...    .|...|:.|:..|.:.|| .:.:.:...:....|.::..:
Mouse   256 AVLVEKKRHKVSTAEKLEDCM----DFATDLIFAERRGDLTKE-NVNQCILEMLIAAPDTMSVTL 315

  Fly   315 SFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTN 379
            .|.|..::.:.|::....:|...:.|:.   :..:..:..:..:|..|.|::|..|.|.|:.|..
Mouse   316 YFMLLLVAEYPEVEAAILKEIHTVVGDR---DIKIEDIQNLKVVENFINESMRYQPVVDLVMRRA 377

  Fly   380 RNPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRR 444
            .....|:|..|.|.|.:|:.:..| :..:||..|..|..|.||.   ||....|:  ||..|||.
Mouse   378 LEDDVIDGYPVKKGTNIILNIGRM-HRLEYFPKPNEFTLENFEK---NVPYRYFQ--PFGFGPRG 436

  Fly   445 CIAEKFAMYQMKALLSQLLRRFEILP----AVDGLPPGIND---HSRED 486
            |..:..||..||.:|..|||||::..    .::.:|.. ||   |..||
Mouse   437 CAGKYIAMVMMKVVLVTLLRRFQVKTLQKRCIENIPKK-NDLSLHPNED 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	89/414 (21%)
Cyp19a1	NP_001335100.1	p450	48..488	CDD:306555	95/439 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845265
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950