Protein Alignment Cyp4ad1 and Cyp4aa1

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: XP_313368.6
• Gene: Cyp4aa1 / 1274272
• VectorBaseID: AGAMI1_007136
• Length: 498
• Species: Anopheles gambiae
• Alignment Length: 529
• Identity: 143/529 - (27%)
• Similarity: 248/529 - (46%)
• Gaps: 71/529 - (13%)

  Fly     6 IAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPFVGNLFQFGLKPAEYPKKVLQYCRKYDF 70
            :.:||..:|::    ||:....:..:...:|||..||.:||......|.. ..:::.|..:.|..
Mosquito    19 LTLILVCVLLY----IFSDYLKICALAFRLPGPKSYPIIGNCLDIARKDL-ITREMAQAYKNYGP 78

  Fly    71 QGFRSLVFLQYHMMLSDPAEIQNILSSSSLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQKLYAP 135
            .. |..:|:....::.||.:::.||||.....|...|..|..:||.||:||||.:|..|:||..|
Mosquito    79 LA-RVWIFVFPMFVVFDPNDLKVILSSKKHTNKSMFYKLLHNFLGRGLITSSGHKWSSHRKLIQP 142

  Fly   136 AFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGET 200
            :|..:.:|.::.....:....:.|   |...:.|.:..|.|..|.|||:.|...|....|::.:.
Mosquito   143 SFNIAILEKFIDTFTDSASFLIDK---LPKEETVLNVTEYVNNCVLDILNEAVLGVPVKSVDKKE 204

  Fly   201 SD----LHGAIKDLCDVVQERTFSIVKRFDALFRLT---SYYMKQRRALSLLRSELNRIISQRRH 258
            .:    ..|.:     |...|.......|:::::||   :..:.|::.|    .:.:|.:.:||.
Mosquito   205 MEQSPFRQGKV-----VAPYRITHPWLLFNSIYKLTDAATAELNQKKQL----DDFSRKMIRRRR 260

  Fly   259 QL-----AAENTCQQGQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIFTGHDPIAAAISFTL 318
            ::     .::..|         .||.::....:.....|.:||:|..||:..|.|.:.||::|||
Mosquito   261 EILKTLSPSDRRC---------LLDFMIEISNENPDFTEDDIIDEACTFMLAGQDSVGAAVAFTL 316

  Fly   319 YTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPI 383
            :.|:||.:.|.|..||..|..|.:.:.......:.::.:||..|:|:|||||||||:||.....:
Mosquito   317 FLLARHQDQQAKCYEEIERHIGTDCSKPPSAEGIRELRHLEACIKESLRLYPSVPLMARKIGEDV 381

  Fly   384 DINGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERF------ENPTGNVGIEAFKSVPFSAGP 442
            .:....:...|.:::...|....|..:.||..|.||||      :||        :..:||||||
Mosquito   382 RVGKYNLPTGTEIMILPYATHRLEHIYPDPERFDPERFGDGAPHQNP--------YAFLPFSAGP 438

  Fly   443 RRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSEN 507
            |.||..|||..:||.:::::|:.|.:.||     ||           :.|..|:  .|:||::..
Mosquito   439 RNCIGYKFAYIEMKTVIARVLQNFHLSPA-----PG-----------KEEVQPI--FRMTLRARG 485

  Fly   508 GIQIRLRKR 516
            |:.:::..|
Mosquito   486 GLWVKMTPR 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	127/455 (28%)
Cyp4aa1	XP_313368.6	None