Protein Alignment Cyp4ad1 and Cyp4f15

DIOPT Version :9

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_598888.1
• Gene: Cyp4f15 / 106648
• MGIID: 2146921
• Length: 534
• Species: Mus musculus
• Alignment Length: 547
• Identity: 154/547 - (28%)
• Similarity: 265/547 - (48%)
• Gaps: 79/547 - (14%)

  Fly     1 MFLIAIAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYP-FVGNLFQFGLKPAEYP-KKVLQ 63
            :.||..:.:||.:|....: .:....|:..    .|.|..:. |:|:|..  :.|.|:. |:|..
Mouse    27 LLLIGASWLLARVLTQTYI-FYRTYHHLCD----FPQPPKWNWFLGHLGM--ITPTEHGLKEVTN 84

  Fly    64 YCRKYDFQGFRS----LVFLQYHMMLSDPAEIQNIL-SSSSLLYKEHL-YSFLRPWLGDGLLTSS 122
            ....|. |||.:    ::.:   :.|..|..|:::| :|:|:..||.: ||||:||||||||.|.
Mouse    85 LVATYP-QGFMTWLGPIIPI---ITLCHPDIIRSVLNASASVALKEVVFYSFLKPWLGDGLLLSD 145

  Fly   123 GARWLKHQKLYAPAFERSAIEGYLRVVH-------------RTGGQFVQKLDVLSDTQEVFDAQE 174
            |.:|..|:::..|||..:.::.|:::.:             .:||.  .:|||.          |
Mouse   146 GDKWSSHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQHLASGGS--ARLDVF----------E 198

  Fly   175 LVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSYYMKQR 239
            .::..|||.: :.......|:.....|:...||.:|..:|.:|...::...|:|::||....:..
Mouse   199 NISLMTLDSL-QKCVFSFDSNCQENPSEYISAILELSALVTKRYHQLLLHIDSLYQLTCSGRRFH 262

  Fly   240 RALSLLRSELNRIISQRRHQLAA--ENTCQQGQPINK--PFLDVLLTAK-LDGKVLKEREIIEEV 299
            :|..|:.|..:.:|..||..|.:  |:...:.:..:|  .|:||||.:| .|||.|.:.:|..|.
Mouse   263 KACHLVHSFTDAVIQDRRRTLPSKHEDDVLKAKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEA 327

  Fly   300 STFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLA-------RLDQMHY 357
            .||:|.|||..|:.:|:.||.|:||.|.|::..:|.:.:..:..:.|.:.:       .|.|:.:
Mouse   328 DTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRDRESTEIECSCAVFLRDDLAQLPF 392

  Fly   358 LELIIRETLRLYPSVPLIARTNRNPIDI-NGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERF 421
            |.:.|:|:|||:|.|.:|:|.....|.: :|..:.|....|:.:.|..:|...:.||..:.|.||
Mouse   393 LTMCIKESLRLHPPVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRF 457

  Fly   422 ENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSRED 486
            : |...........:|||||||.||.:.|||.:||..|:..|.||.:||
Mouse   458 D-PENIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRVLP---------------- 505

  Fly   487 CVPQSEYDPVLNIRVTLKSENGIQIRL 513
                .:.:|.....:.|::|.|:.:|:
Mouse   506 ----DDKEPRRKPELILRAEGGLWLRV 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	141/467 (30%)
Cyp4f15	NP_598888.1	p450	57..526	CDD:278495	147/508 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845217
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.650