Protein Alignment Cyp4ad1 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 528
• Identity: 130/528 - (24%)
• Similarity: 231/528 - (43%)
• Gaps: 59/528 - (11%)

  Fly     6 IAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPF-VGNLFQFGLKPAEYPKKVLQ--YCRK 67
            :.||:..::.|  :....||.:|....:.||||....| :|::..  |..||....|:.  :...
 Frog    18 LLIIIGAVVAF--LAYCAYIKYMHLKYDDIPGPPRDSFLLGHIPT--LSKAEENYSVVHDLFLHW 78

  Fly    68 YDFQG--FRSLVFLQYHMMLSDPAEIQNILSSSSLLYKEHLYS-----FLRPWLGDGLLTS-SGA 124
            .:..|  |:..:..:..:..:.|..::..|.||......:.|:     |.:.:||.||||. ...
 Frog    79 AEIYGPVFKINILHRVMIYSTSPESVKECLMSSKYPKDPYTYNQLFNLFGKRFLGKGLLTDPDHD 143

  Fly   125 RWLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENAT 189
            .|...:::..|||..:.::..:.:.:....|.::||:..:|..:......::.:.|||::.:.|.
 Frog   144 HWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMMEKLEEKADGHQEVSMHSIINRVTLDVITKVAF 208

  Fly   190 GQDSSSLNGETSDLHGAI-KDLCDVVQERTFSIVKRFDALFRLTSYYMKQRRALSLLRSELNRII 253
            |.|...:.|..:|...|| |.|..:::......::.|.   :..::..:.:.:..|||......|
 Frog   209 GMDLGLVEGNKTDFPNAISKVLTGMMRYMQNPYMQYFP---KHWAFVREVQESADLLRKTGKECI 270

  Fly   254 SQRRHQLAAENTCQQGQPINKPFL-DVLLTAKLDGKVLKEREIIEEVSTFIFTGHDPIAAAISFT 317
            |||:..:      |.|:.:.|..| .:|..|:|: ..|.:..:::...||...|.:..|..:|||
 Frog   271 SQRKKAM------QNGEELPKDILTKILQCAELE-NALDDEIMLDNFITFFIAGQETTANQLSFT 328

  Fly   318 LYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNP 382
            :..|:|..||..|...|...:.|  |..:.....:..::|:..:::|:||.||..|..:|..:..
 Frog   329 VMELTRQPEIMTKLRMEVDEVIG--FKRDISYDDIQNLNYMTQVLKESLRFYPPGPGTSRYLKED 391

  Fly   383 IDINGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFE----NPTGNVGIEAFKSVPFSAGPR 443
            ....|.|:....::......||..||:|.|||.|.||||.    .|       .|...||:.|||
 Frog   392 TIFEGIKIPGGVSITFNTYVMGRMEKFFQDPCKFDPERFHPAAVKP-------YFCYFPFALGPR 449

  Fly   444 RCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENG 508
            .|:.:.|:..:.|.:||:|::||| ...|.|...||.|..                  ||:..:|
 Frog   450 SCLGQIFSQLEAKVILSKLIQRFE-FELVPGQSFGIKDTG------------------TLRPRDG 495

  Fly   509 IQIRLRKR 516
            :...|:.|
 Frog   496 VVCTLKSR 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	111/449 (25%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	112/463 (24%)