Protein Alignment Cyp4ad1 and cyp4b1

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001120073.1
• Gene: cyp4b1 / 100145080
• XenbaseID: XB-GENE-5924259
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 524
• Identity: 146/524 - (27%)
• Similarity: 251/524 - (47%)
• Gaps: 49/524 - (9%)

  Fly     5 AIAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPFVGNLFQFGLKPAEYPKKVLQYCRKYD 69
            |:..:||.:|  |..:::........|.:..|||..:..:||:.|. .:..:....::.:..|..
 Frog    21 ALLCLLAVLL--KATQLYLSQKRQENIFKQFPGPPRHWLLGNVDQI-RRDGKDLDLLVNWTHKNG 82

  Fly    70 ------FQGFRSLVFL---QYHMMLSDPAEIQNILSSSSLLYKEHLYSFLRPWLGDGLLTSSGAR 125
                  |..|.|.:||   .|..::....|.::.:|          |.||.||:|.|||..:|.:
 Frog    83 GAFPVWFGNFSSFLFLTHPDYAKVIFGREEPKSSIS----------YDFLVPWIGKGLLVLTGPK 137

  Fly   126 WLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATG 190
            |.:|::|..|.|....::.|:.::.:.....:...:.|...|:..:..:.::..|||.:.:.|..
 Frog   138 WFQHRRLLTPGFHYDVLKPYVNLISKCTTDMLDNWEKLITKQKTVELFQHLSLMTLDSIMKCAFS 202

  Fly   191 QDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSYYMKQRRALSLLRSELNRIISQ 255
            .||:......:....|:.||..|...|........|.:|.|:.:..:.|:|..:.....:::|.|
 Frog   203 YDSNCQKDSNNAYIKAVFDLSYVANLRLRCFPYHNDTVFYLSPHGYRFRKACRITHEHTDKVIQQ 267

  Fly   256 RRHQLAAENTCQQ-GQPINKPFLDVLLTAKLD-GKVLKEREIIEEVSTFIFTGHDPIAAAISFTL 318
            |:..:..|...:: .|..:..|||:||.|:.: |..|.:.::..||.||:|.|||..|:.||:.|
 Frog   268 RKESMKLEKELEKIQQKRHLDFLDILLFARDEKGHGLSDDDLRAEVDTFMFEGHDTTASGISWIL 332

  Fly   319 YTLSRHSEIQQKAAEEQRRIFGENFAGE-ADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNP 382
            |.::::.|.|||..||.:.:.|:....| .||.::.   |..:.|:|:||:||.||.:||..|||
 Frog   333 YCMAKYPEHQQKCREEIKEVLGDRQIMEWEDLGKIP---YTNMCIKESLRMYPPVPGVARQLRNP 394

  Fly   383 ID-INGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRCI 446
            :. .:|..|...|.:.:.:.|:..|...::||..|.|.|| :|..:....:...:||:||||.||
 Frog   395 VTFFDGRSVPAGTLIGLSIYAIHKNPAVWEDPEVFNPLRF-SPENSANRHSHAFLPFAAGPRNCI 458

  Fly   447 AEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENGIQI 511
            .:.|||.:||..::..|.||.:.|.::..|..|         ||          :.|||:|||.:
 Frog   459 GQNFAMNEMKVAVALTLNRFHLAPDLENPPIKI---------PQ----------LVLKSKNGIHV 504

  Fly   512 RLRK 515
            .|.|
 Frog   505 HLTK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	130/444 (29%)
cyp4b1	NP_001120073.1	CYP4B-like	71..505	CDD:410771	132/466 (28%)