Protein Alignment Cyp4ad1 and Cyp4a32

DIOPT Version :9

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 529
• Identity: 147/529 - (27%)
• Similarity: 258/529 - (48%)
• Gaps: 54/529 - (10%)

  Fly     2 FLIAIAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPFVGNLFQFGLKPAEYPKKVLQYCR 66
            ||...:::...:|:.|.|:.:.:...:...::..|.|..:.|.|: .||  |..:..|:|:....
Mouse    18 FLQVASVLGLLLLLVKAVQFYLHRKWLLKALQQFPSPPFHWFFGH-EQF--KGEQELKEVVSCIE 79

  Fly    67 KYD------FQGFRSLVFLQYHMMLSDPAEIQNILSSSSLLYKEHLYSFLRPWLGDGLLTSSGAR 125
            .:.      |.|..:      ::.:.||..::.||..|. .....:|..|.||:|.|||..:|..
Mouse    80 HFPSAFPCWFWGSNA------YLTVYDPDYMKVILGRSD-PKANGIYRLLAPWIGYGLLLLNGQP 137

  Fly   126 WLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENA-T 189
            |.:|:::..|||....::.|::.:..:....:.|.:.|:......:..:.::..|||.|.:.| :
Mouse   138 WFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLAGQDSSIEIFQHISLMTLDTVMKCAFS 202

  Fly   190 GQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSYYMKQRRALSLLRSELNRIIS 254
            .:.|..::|.......||.||.::...|..:|..:.|.::||:|.....::|..|.....:.:|.
Mouse   203 HKGSVQVDGNYKTYLQAIGDLNNLFHSRVRNIFHQNDTIYRLSSNGRLAKQACQLAHDHTDGVIK 267

  Fly   255 QRRHQLAAENTCQQGQPINK----PFLDVLLTAKLD-GKVLKEREIIEEVSTFIFTGHDPIAAAI 314
            .|:.||..|...:.   |.|    .|||:||.|::: |..:.::::..||.||:|.|||..|:.:
Mouse   268 MRKDQLQDEGELEN---IKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGV 329

  Fly   315 SFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTN 379
            |:..|.|:.|.|.||:..||.:.:.|:..:...|  .|||:.|..:.|:|.|||||.||.|.|..
Mouse   330 SWIFYALATHPEHQQRCREEVQSLLGDGSSITWD--HLDQIPYTTMCIKEALRLYPPVPGIVREL 392

  Fly   380 RNPIDI-NGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERF--ENPTGNVGIEAFKSVPFSAG 441
            ...:.. :|..:.|...|.:.:..:.:|.|.:.:|..|.|.||  ::|.     .:...:|||.|
Mouse   393 STSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPR-----HSHSFLPFSGG 452

  Fly   442 PRRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSE 506
            .|.||.::|||.::|.:::..|..||:||          |.:|   ||    :|:  .|:.|||:
Mouse   453 ARNCIGKQFAMSELKVIVALTLLHFELLP----------DPTR---VP----EPL--ARIVLKSK 498

  Fly   507 NGIQIRLRK 515
            |||.:.|:|
Mouse   499 NGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	126/448 (28%)
Cyp4a32	NP_001093651.1	p450	52..503	CDD:278495	140/489 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845129
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650