Protein Alignment CG2121 and UNC93B1

DIOPT Version :9

• Sequence 1: NP_001137618.1
• Gene: CG2121 / 35814
• FlyBaseID: FBgn0033289
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_112192.2
• Gene: UNC93B1 / 81622
• HGNCID: 13481
• Length: 597
• Species: Homo sapiens
• Alignment Length: 519
• Identity: 100/519 - (19%)
• Similarity: 204/519 - (39%)
• Gaps: 96/519 - (18%)

  Fly    58 PNGDNKVNQRHYEPAERFIITKNVVVIGLAFMIHFTAFHGTSNLQSSVNADKALGTTTLAVIYGS 122
            ||.:.:..:|.|...:|..:.|||:......|:.:..:.|...:|..::.|:    |...|.||:
Human    41 PNYNEEEEERRYYRRKRLGVLKNVLAASAGGMLTYGVYLGLLQMQLILHYDE----TYREVKYGN 101

  Fly   123 LILSNI-----------------FLPMTVIRWFGCRLTMALALFAYMPYIAAQFYPRFETLIPAA 170
            :.|.:|                 :.|: :||:||.:..|.||:..|..:::..::.|:.||:|:|
Human   102 MGLPDIDSKMLMGINVTPIAALLYTPV-LIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSA 165

  Fly   171 LMVGFGGGPLWCSKCTYLSTVSEALTQV--------RGNKSRKDVNT-----VKFFGLFFIFYQM 222
            :.:|....|||.|...|::.:::...:.        :|.|.|....:     :.|..:|:.|:.:
Human   166 VALGMAIVPLWASMGNYITRMAQKYHEYSHYKEQDGQGMKQRPPRGSHAPYLLVFQAIFYSFFHL 230

  Fly   223 AQVWGNL-----ISSSVLTLSAPA--AQSAANDS------FELEVQRELERNRVAELCGARFCPG 274
            :.....|     ::..:..|:...  .||...:|      |...|.|.|.|
Human   231 SFACAQLPMIYFLNHYLYDLNHTLYNVQSCGTNSHGILSGFNKTVLRTLPR-------------- 281

  Fly   275 VGAEANPNLVPPAPEQIQLLNSIFLTC--MAAAVVMMIFGVSSLKRYGVKRGDTGDGMSGLKLLT 337
                 :.||:        ::.|:.:..  :|..:|:.:.|.:......:.....|.|    .:..
Human   282 -----SGNLI--------VVESVLMAVAFLAMLLVLGLCGAAYRPTEEIDLRSVGWG----NIFQ 329

  Fly   338 VTINLLRKRRQILMLPITMFIGLEEAFLAVDFTRSFVACGWGISRIGFAMICFGVANAVAAGIAG 402
            :....:|..|...::|..::.|.|..|........:..|..|:.|:.:.::.:.: .|.||.:.|
Human   330 LPFKHVRDYRLRHLVPFFIYSGFEVLFACTGIALGYGVCSVGLERLAYLLVAYSL-GASAASLLG 393

  Fly   403 ALVERIGRVTLAALCAVVNLCLLTYMYTW----EAREGDYMSYCTFAAVWGICDGVWLVVVNAFY 463
            .|...:.|.......|.|:|.|...::.|    ...:..::.|.. ||:||:...:....::...
Human   394 LLGLWLPRPVPLVAGAGVHLLLTFILFFWAPVPRVLQHSWILYVA-AALWGVGSALNKTGLSTLL 457

  Fly   464 GILF-----PNHLIAAYSNFRLWESTGSVIGYVISSQLCTSTKLVILIIFILVGCVGYGLIEYR 522
            |||:     .:.:...|.    |....::....:.|.|....||.:|::.::...|.|..:|.:
Human   458 GILYEDKERQDFIFTIYH----WWQAVAIFTVYLGSSLHMKAKLAVLLVTLVAAAVSYLRMEQK 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2121	NP_001137618.1	MFS	84..>189	CDD:304372	30/121 (25%)
		MFS_1	<296..476	CDD:284993	34/190 (18%)
UNC93B1	NP_112192.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		MFS_unc93B1	64..520	CDD:340966	93/496 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..597

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3097
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810