Protein Alignment CG2121 and UNC93A

DIOPT Version :9

• Sequence 1: NP_001137618.1
• Gene: CG2121 / 35814
• FlyBaseID: FBgn0033289
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_061847.2
• Gene: UNC93A / 54346
• HGNCID: 12570
• Length: 457
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 144/444 - (32%)
• Similarity: 240/444 - (54%)
• Gaps: 22/444 - (4%)

  Fly    79 KNVVVIGLAFMIHFTAFHGTSNLQSSVNADKALGTTTLAVIYGSLILSNIFLPMTVIRWFGCRLT 143
            :||:|:...|::.|||:.|..:||||:.:::.||.|.|:.:||.::||::|||..:|...||:.|
Human     6 RNVLVVSFGFLLLFTAYGGLQSLQSSLYSEEGLGVTALSTLYGGMLLSSMFLPPLLIERLGCKGT 70

  Fly   144 MALALFAYMPYIAAQFYPRFETLIPAALMVGFGGGPLWCSKCTYLSTVSEALTQVRGNKSRKDVN 208
            :.|::..|:.:....|:..:.||||.::::|.|..|||.::||||:.......:..|.:.:..||
Human    71 IILSMCGYVAFSVGNFFASWYTLIPTSILLGLGAAPLWSAQCTYLTITGNTHAEKAGKRGKDMVN 135

  Fly   209 TVKFFGLFFIFYQMAQVWGNLISSSVLTLSAPAAQSAANDSFELEVQRELERNRVAELCGARFCP 273
              ::||:||:.:|.:.||||||||.|.      .|:.:        |..|...::.. |||..|.
Human   136 --QYFGIFFLIFQSSGVWGNLISSLVF------GQTPS--------QETLPEEQLTS-CGASDCL 183

  Fly   274 GVGAEANPNLVPPAPEQIQLLNSIFLTCMAAAVVMMIFGVSSLKRYGVKRGDTGDGMS--GLKLL 336
            ......| :...|:.:.:..|..|:......||:|:...:..::  .|:|...|:..|  ....|
Human   184 MATTTTN-STQRPSQQLVYTLLGIYTGSGVLAVLMIAAFLQPIR--DVQRESEGEKKSVPFWSTL 245

  Fly   337 TVTINLLRKRRQILMLPITMFIGLEEAFLAVDFTRSFVACGWGISRIGFAMICFGVANAVAAGIA 401
            ..|..|.|.:|..|::.:.::.||::.||:.::|||:|.|..||..:|:.||||...:|:.:.:.
Human   246 LSTFKLYRDKRLCLLILLPLYSGLQQGFLSSEYTRSYVTCTLGIQFVGYVMICFSATDALCSVLY 310

  Fly   402 GALVERIGRVTLAALCAVVNLCLLTYMYTWEAREGDYMSYCTFAAVWGICDGVWLVVVNAFYGIL 466
            |.:.:..||..|..|.||.::..:..:..|..|......:..|:.:||:.|.||....||.||:|
Human   311 GKVSQYTGRAVLYVLGAVTHVSCMIALLLWRPRADHLAVFFVFSGLWGVADAVWQTQNNALYGVL 375

  Fly   467 FPNHLIAAYSNFRLWESTGSVIGYVISSQLCTSTKLVILIIFILVGCVGYGLIE 520
            |.....||::|:||||:.|.||.:..|..||...||.||:..:.:..|.|||:|
Human   376 FEKSKEAAFANYRLWEALGFVIAFGYSMFLCVHVKLYILLGVLSLTMVAYGLVE 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2121	NP_001137618.1	MFS	84..>189	CDD:304372	39/104 (38%)
		MFS_1	<296..476	CDD:284993	54/181 (30%)
UNC93A	NP_061847.2	MFS	8..428	CDD:119392	141/439 (32%)
		MFS_1	11..398	CDD:284993	128/406 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144965
Domainoid	1	1.000	100	1.000	Domainoid score	I7022
eggNOG	1	0.900	-	-		E1_KOG3097
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4703
OMA	1	1.010	-	-		QHG54908
OrthoDB	1	1.010	-	-		D1145833at2759
OrthoFinder	1	1.000	-	-		FOG0003220
OrthoInspector	1	1.000	-	-		otm41213
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19444
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2890
SonicParanoid	1	1.000	-	-		X2635
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.800