DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2121 and Unc93b1

DIOPT Version :9

Sequence 1:	NP_001137618.1	Gene:	CG2121 / 35814	FlyBaseID:	FBgn0033289	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_001101983.1	Gene:	Unc93b1 / 361689	RGDID:	1311984	Length:	630	Species:	Rattus norvegicus

Alignment Length:	528	Identity:	96/528 - (18%)
Similarity:	205/528 - (38%)	Gaps:	97/528 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 PNGDNKVNQRHYEPAERFIITKNVVVIGLAFMIHFTAFHGTSNLQSSVNADKA------------ 110
            ||.:.:..:|.|...:|..:.|||:.......:.:..:.|...:|..::.|:.
  Rat    62 PNYNEEEEERRYYRRKRLGVVKNVLAASTGGTLTYGVYLGLLQMQLILHYDETYREVKYGNMGLP 126

  Fly   111 -------LG---TTTLAVIYGS-LILSNIFLPMTVIRWFGCRLTMALALFAYMPYIAAQFYPRFE 164
                   :|   |...|::|.. ||...:.:.:.:.|:||.:..|.||:..|..:::..::.|:.
  Rat   127 DIDSKMLMGINVTPIAALLYTPVLIRPKVLMSLPLYRFFGTKWMMFLAVGIYALFVSTNYWERYY 191

  Fly   165 TLIPAALMVGFGGGPLWCSKCTYLSTVSEALTQVRGNKSRKDVN-------------TVKFFGLF 216
            ||:|:|:.:|....|||.|...|::.:|:...:....|.:.:..             .:.|..:|
  Rat   192 TLVPSAVALGMAIVPLWASMGNYITRMSQKYYEYSHYKEQDEQGPQQRPPRGSHAPYLLVFQAIF 256

  Fly   217 FIFYQMAQVWGNL------------ISSSVLTLSAPAAQS-AANDSFELEVQRELERNRVAELCG 268
            :.|:.::.....|            ::.::..:.:...:| ...:.|...|.|.|.|:|
  Rat   257 YSFFHLSFACAQLPMVYFLNHYLYDLNHTLFNVKSCGTKSYGILNGFNKTVLRTLPRSR------ 315

  Fly   269 ARFCPGVGAEANPNLVPPAPEQIQLLNSIFLTC--MAAAVVMMIFGVSSLKRYGVKRGDTGDGMS 331
                         ||:        ::.|:.:..  :|..:|:.:.|.:......:.....|.|
  Rat   316 -------------NLI--------VVESVLMAVAFLAMLLVLGLCGAAYRPTEEIDLRSVGWG-- 357

  Fly   332 GLKLLTVTINLLRKRRQILMLPITMFIGLEEAFLAVDFTRSFVACGWGISRIGFAMICFGVANAV 396
              .:..:....:|..|...::|..::.|.|..|....||..:..|..|:.|:.:.:|.:.: .|.
  Rat   358 --NIFQLPFKHVRDFRLRHLVPFFIYSGFEVLFACTGFTLGYGVCSMGLERLAYLLIAYSL-GAS 419

  Fly   397 AAGIAGALVERIGRVTLAALCAVVNLCLLTYMYTW----EAREGDYMSYCTFAAVWGICDGVWLV 457
            ||.:.|.|...:.|.......|.::|.|...::.|    ...:..::.|.. ||:||:...:...
  Rat   420 AASVLGLLGLWLPRSVPLVAGAGLHLLLTLSLFFWAPAPRVLQHSWIFYFV-AALWGVGSALNKT 483

  Fly   458 VVNAFYGILFPN--HLIAAYSNFRLWESTGSVIGYVISSQLCTSTKLVILIIFILVGCVGYGLIE 520
            .::...|||:.:  .....::.:..|::....:.| :.|.|....||.:|::.::.....|
  Rat   484 GLSTLLGILYEDKERQDFIFTIYHWWQAVAIFVVY-LGSSLPMKAKLAVLLVTLVAAATSY---- 543

  Fly   521 YRFWQKQK 528
              .|.:.|
  Rat   544 --LWMENK 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2121	NP_001137618.1	MFS	84..>189	CDD:304372	27/127 (21%)
CG2121	NP_001137618.1	MFS_1	<296..476	CDD:284993	36/187 (19%)
Unc93b1	NP_001101983.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3097
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810