DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2121 and SPAC922.05c

DIOPT Version :9

Sequence 1:	NP_001137618.1	Gene:	CG2121 / 35814	FlyBaseID:	FBgn0033289	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_595005.1	Gene:	SPAC922.05c / 2543555	PomBaseID:	SPAC922.05c	Length:	504	Species:	Schizosaccharomyces pombe

Alignment Length:	463	Identity:	90/463 - (19%)
Similarity:	151/463 - (32%)	Gaps:	131/463 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 ITKNVVVIGLAFMI--HFTAFHGTSNLQSSVNADKALGTTTLAVIYGSLILSNIFLPMTVIRWFG 139
            :|:.::|..:.|:.  .|.|..|... ...||||.|  ......:| |......|...::....|
pombe    60 LTQTIIVSWVCFLCPGMFNALSGLGG-GGEVNADVA--NDANVALY-STFAGLGFFAGSICNLIG 120

  Fly   140 CRLTMALALFAYMPYIAA-----QFYPRFETLIPAALMVGFGGGPLWCSKCTYLSTVSEALTQVR 199
            .:||:|:....|..|.|:     ..|.| ..:|.....:|...|.||.::...:.:..
pombe   121 VKLTLAIGGTGYSVYTASLLCYKHVYNR-GFVIFGGCYLGLTAGMLWAAQGAVIMSYP------- 177

  Fly   200 GNKSRKDVNTVKFFGLFFIFYQMAQVWGNLISSSVLTLSAPAAQ---SAANDSFELEVQRELERN 261
                 ::.|..::..:|:..:.:..|.|:::         |.||   |:.|.
pombe   178 -----REENKARYIAIFWGIFNLGAVIGSIV---------PLAQTMHSSVNS------------- 215

  Fly   262 RVAELCGARFCPGVGAEANPNLVPPAPEQIQLLNSIFLTCMAAAVVMMIFGVSSLKRYGVKRGDT 326
                       .|.|..|.                 |:..||....:.:|.||..|.  ||.
pombe   216 -----------VGDGTYAG-----------------FIVLMAVGSALALFMVSPEKT--VKE--- 247

  Fly   327 GDG--------MSGLKLLTVTINLLRKRRQILMLPITMFIGLEEAFLAVDFTRSFVACGWGISRI 383
             ||        |...|.|...:..|.|...:|:| ..||.. ...|....| ..|....:.|...
pombe   248 -DGKFVHIEKSMGWKKELLGLVQTLYKEYWVLLL-FPMFFS-SNWFTTYQF-NDFNLAYFNIRTR 308

  Fly   384 GFAMICFGVANAVAAGIAGALV--ERIGRVTLAAL---CAVVNLCLL-------TYMYTWEA-RE 435
            ....:.:..|..:.:.:|...:  :|..||..|.:   ...|.:|::       ...||.:: .|
pombe   309 SLNNLLYWFAQIMGSAVAALFLDWQRFNRVIRARVGWGLVFVLICVIWGGGLAFQLKYTRKSVAE 373

  Fly   436 GD----------YMSYCTFAAVWGICDGV------WLVVVNAFYGILF-PNHLIAAYSNF-RLWE 482
            .|          |..|......:|:.|.:      |::      |.|. ..:.:|.|..| :..:
pombe   374 SDFVVTDFTHRGYTGYAFLYIFYGMLDAIFQSYAYWII------GSLSNDTNKLAVYMGFYKSLQ 432

  Fly   483 STGSVIGY 490
            |.|:.|.|
pombe   433 SAGAAITY 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2121	NP_001137618.1	MFS	84..>189	CDD:304372	26/111 (23%)
CG2121	NP_001137618.1	MFS_1	<296..476	CDD:284993	44/217 (20%)
SPAC922.05c	NP_595005.1	MFS_1	99..438	CDD:284993	77/417 (18%)
SPAC922.05c	NP_595005.1	MFS	<101..202	CDD:304372	21/114 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910