DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2121 and unc93a.2

DIOPT Version :9

Sequence 1:	NP_001137618.1	Gene:	CG2121 / 35814	FlyBaseID:	FBgn0033289	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	XP_002931523.1	Gene:	unc93a.2 / 100170165	XenbaseID:	XB-GENE-5800507	Length:	460	Species:	Xenopus tropicalis

Alignment Length:	452	Identity:	170/452 - (37%)
Similarity:	260/452 - (57%)	Gaps:	20/452 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 KNVVVIGLAFMIHFTAFHGTSNLQSSVNADKALGTTTLAVIYGSLILSNIFLPMTVIRWFGCRLT 143
            ||::::...|::.||||.|..:||||:|:|:.||..:|:||||:||:|::|:|..:|:..||:.|
Frog     5 KNILIVSFGFLLLFTAFGGLQSLQSSLNSDEGLGVASLSVIYGALIISSVFVPSILIKKIGCKWT 69

  Fly   144 MALALFAYMPYIAAQFYPRFETLIPAALMVGFGGGPLWCSKCTYLSTVSEALTQVRGNKSRKDVN 208
            :..::..|:.|....||..:.||||.:|::||||.|||.:|||||:.......:.:|..::..||
Frog    70 IVASMCCYITYSLGNFYASWYTLIPTSLILGFGGAPLWAAKCTYLTESGNRYAEKKGKLAKDIVN 134

  Fly   209 TVKFFGLFFIFYQMAQVWGNLISSSVLTLSAPAAQSAANDSFELEVQRELERNRVAELCGARFCP 273
              ::|||||:.:|.:.||||||||.:....:||   .:|:||.           ....|||..||
Frog   135 --QYFGLFFLIFQSSGVWGNLISSLIFGQDSPA---GSNNSFP-----------DYSHCGANDCP 183

  Fly   274 GVGAEANPNLVPPAPEQIQLLNSIFLTCMAAAVVM--MIFGVSSLKRYGVKRGDTGDGMSGLKLL 336
            |.........:.|....|..|..::......||::  :.....:|:...:|.|...:  |.:|.:
Frog   184 GSNFGNGTGSIKPTQSLIYTLLGVYTGSGVLAVILIAVFLDTINLRTDQLKPGTKEE--SFIKKI 246

  Fly   337 TVTINLLRKRRQILMLPITMFIGLEEAFLAVDFTRSFVACGWGISRIGFAMICFGVANAVAAGIA 401
            ..||..|:.:||.|::|:||:.|.|:.|||.|:|:|:|.|..||..:|:.||||...|||.:.:.
Frog   247 LATIRHLKDKRQCLLIPLTMYSGFEQGFLAGDYTKSYVTCSLGIHFVGYVMICFAATNAVCSLLF 311

  Fly   402 GALVERIGRVTLAALCAVVNLCLLTYMYTWEAREGDYMSYCTFAAVWGICDGVWLVVVNAFYGIL 466
            |.|.:..||:.|..:.||:|...:..:..|:....|:..:..|.|:|||.|.||....||.||:|
Frog   312 GQLSKYTGRIFLFIMAAVLNAASIIALLLWQPHPNDFAVFFIFPAIWGIADAVWQTQTNALYGVL 376

  Fly   467 FPNHLIAAYSNFRLWESTGSVIGYVISSQLCTSTKLVILIIFILVGCVGYGLIEYRFWQKQK 528
            |..|..||::|:|||||.|.||.|..|:.||.|.||.||:..:|:..|.||.:||..:.:.|
Frog   377 FDEHKEAAFANYRLWESLGFVIAYGYSTFLCVSIKLYILLAVLLIAIVLYGCVEYLEYVEHK 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2121	NP_001137618.1	MFS	84..>189	CDD:304372	48/104 (46%)
CG2121	NP_001137618.1	MFS_1	<296..476	CDD:284993	63/181 (35%)
unc93a.2	XP_002931523.1	MFS_unc93A_like	7..434	CDD:340964	167/444 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54908
OrthoDB	1	1.010	-	-		D1145833at2759
OrthoFinder	1	1.000	-	-		FOG0003220
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19444
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2635
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.030