Protein Alignment pdm3 and POU6F1

DIOPT Version :9

• Sequence 1: NP_001188885.2
• Gene: pdm3 / 35813
• FlyBaseID: FBgn0261588
• Length: 1292
• Species: Drosophila melanogaster
• Sequence 2: XP_016874997.1
• Gene: POU6F1 / 5463
• HGNCID: 9224
• Length: 613
• Species: Homo sapiens
• Alignment Length: 865
• Identity: 240/865 - (27%)
• Similarity: 336/865 - (38%)
• Gaps: 308/865 - (35%)

  Fly   466 SPLNLSVGGEPVATTG-----------PSVAPTSPTHNGGKSKTAKGGSSGNGSGGSSANSGTSS 519
            |..:|:|..:.:..:|           .:..|......|.:...|:|..||:.:..|.| :|.:.
Human     7 SETSLTVNEQVIVMSGHETIRVLEVGVDAQLPAEEESKGLEGVAAEGSQSGDPAEASQA-AGEAG 70

  Fly   520 AQQQQQPDNPSSSSSPHHPLSASSLANVLAAATASPPPSLQAPPASAQMPQLILASGQLVQGVQG 584
                  |||..||                |.||...||.:...||:|     |....|.....|.
Human    71 ------PDNLGSS----------------AEATVKSPPGIPPSPATA-----IATFSQAPSQPQA 108

  Fly   585 AQLLIPTAQGIAVQTILTIPVSPQIPTTEQFLPNAFGAFASYQQQQQQQQQQRDLLPPSLAALQH 649
            :|.|.|          |.:..:||:.|.|
Human   109 SQTLTP----------LAVQAAPQVLTQE------------------------------------ 127

  Fly   650 ATALPQLAQTPTNLLKPNLFSTGVQQLLTALHPELFAAAAATHQQQQQQQQQQVQQQRERERERE 714
                 .||...|.::.|   :..|.|.|  |.|...|...|
Human   128 -----NLATVLTGVMVP---AGAVTQPL--LIPISIAGQVA------------------------ 158

  Fly   715 REREREREREREQHLGIGHLPHSHLAADLRRSAERSP--TAGSPTGGSPGLAAKGPQPPPPGAAF 777
                      .:|.|.:..:|.:.:||        .|  ||.|||||.       .:||..|
Human   159 ----------GQQGLAVWTIPTATVAA--------LPGLTAASPTGGV-------FKPPLAG--- 195

  Fly   778 LLQQQLHIKPETQTHLHHHLQTQSTSAVSSTLPQISLRHPDELTAPQMDLKPLELSASTSPPAPP 842
                                 .|:.:.:::.||           ||.....|::.| ||:.|.||
Human   196 ---------------------LQAAAVLNTALP-----------APVQAAAPVQAS-STAQPRPP 227

  Fly   843 PRHHFGHSLRGSSTVSPKHSPQGRMGGSGGSTTTGMNLSQHHERHDRLERLERQERHERRSHTPT 907
            .:.......:.....:|...||.....:...|.                             .|.
Human   228 AQPQTLFQTQPLLQTTPAILPQPTAATAAAPTP-----------------------------KPV 263

  Fly   908 ATATRASVSSSSSAGHHGGSLPSGRLSPPSSAPSNSAANSISDRGYTSPLFRTHSPQGHALSLGG 972
            .|..:.:|..:      |.:...|.:|..|.........|::    |:|:..:..|        .
Human   264 DTPPQITVQPA------GFAFSPGIISAASLGGQTQILGSLT----TAPVITSAIP--------S 310

  Fly   973 SPRLERDYLGN--GPSSGT---ATSTSSCGAPTAAGS----SATANVLSSINRLNASNGELTITK 1028
            .|.:....|.|  |...||   ..:::|..||..|.|    :.|..:|     ||| .|::
Human   311 MPGISSQILTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLL-----LNA-QGQV---- 365

  Fly  1029 SLGAPTATATRASSASP-----RDDSPGPGPSTSSVSHMQP---------LKLSPSSRSEPPHLS 1079
                   .||.|||..|     |..|....|:.|.|..:||         :..||:..::|...:
Human   366 -------IATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASA 423

  Fly  1080 PNGNDNDNDLLMDSPNEPTINQATTNV--------VDGIDLDEIKEFAKAFKLRRLSLGLTQTQV 1136
            |        :.:.....||::|..:::        .|||:|:||:||||.||:||||||||||||
Human   424 P--------IPITCSETPTVSQLVSSLEPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQV 480

  Fly  1137 GQALSVTEGPAYSQSAICSSALAAQMYAAQLSTQQQNMFEKLDITPKSAQKIKPVLERWMKEAEE 1201
            ||||:.||||||||||||                   .|||||||||||||:|||||:|:.|||
Human   481 GQALTATEGPAYSQSAIC-------------------RFEKLDITPKSAQKLKPVLEKWLNEAE- 525

  Fly  1202 SHWNRYKSGQNHLTDYIGVEPSKKRKRRTSFTPQALELLNAHFERNTHPSGTEITGLAHQLGYER 1266
               .|.:.||.:|.:::|.||||||||||||||||:|.|||:||:|..|:|.|||.:|.:|.|:|
Human   526 ---LRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDR 587

  Fly  1267 EVIRIWFCNKRQALKNTVRM 1286
            ||:|:||||:||.||||.::
Human   588 EVVRVWFCNRRQTLKNTSKL 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm3	NP_001188885.2	Pou	1108..1200	CDD:304656	60/91 (66%)
		Homeobox	1228..1281	CDD:278475	34/52 (65%)
POU6F1	XP_016874997.1	Atrophin-1	<41..407	CDD:331285	116/598 (19%)
		POU	451..525	CDD:197673	60/92 (65%)
		Homeobox	549..602	CDD:306543	34/52 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I8527
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004074
OrthoInspector	1	1.000	-	-		otm40354
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11636
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4954
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	6.040