Protein Alignment pdm3 and POU5F1

DIOPT Version :9

• Sequence 1: NP_001188885.2
• Gene: pdm3 / 35813
• FlyBaseID: FBgn0261588
• Length: 1292
• Species: Drosophila melanogaster
• Sequence 2: NP_002692.2
• Gene: POU5F1 / 5460
• HGNCID: 9221
• Length: 360
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 90/381 - (23%)
• Similarity: 141/381 - (37%)
• Gaps: 112/381 - (29%)

  Fly   921 AGHHGGSLPSGRLSPPSSAPSNSAANSISDRGYTSPLFRTHSPQGHALSLGGSPRLERDYLGNGP 985
            |||.....   ..|||.....:....  .:.|:..|  ||.      ||..|.|        .||
Human     2 AGHLASDF---AFSPPPGGGGDGPGG--PEPGWVDP--RTW------LSFQGPP--------GGP 45

  Fly   986 SSGTATSTSS--------------CGAPTAAGSSATANVLSSINRLNASNGELTITKSLG-APTA 1035
            ..|......|              ||.....|......::        ..|.|..::..| |...
Human    46 GIGPGVGPGSEVWGIPPCPPPYEFCGGMAYCGPQVGVGLV--------PQGGLETSQPEGEAGVG 102

  Fly  1036 TATRASSASPRDDSPGPGPSTSSVSHMQPLKLSPSSRSEPPHLSPNGNDNDNDLLMDSPNEPTIN 1100
            ..:.:..|||                            ||..::|.....:.:.|..:|.|....
Human   103 VESNSDGASP----------------------------EPCTVTPGAVKLEKEKLEQNPEESQDI 139

  Fly  1101 QATTNVVDGIDLDEIKEFAKAFKLRRLSLGLTQTQVGQALSVTEGPAYSQSAICSSALAAQMYAA 1165
            :|...        |:::|||..|.:|::||.||..||..|.|..|..:||:.||
Human   140 KALQK--------ELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTIC----------- 185

  Fly  1166 QLSTQQQNMFEKLDITPKSAQKIKPVLERWMKEAEESHWNRYKSGQNHLTDYIGVE---PSKKRK 1227
                    .||.|.::.|:..|::|:|::|::||:.:         .:|.:....|   .::|||
Human   186 --------RFEALQLSFKNMCKLRPLLQKWVEEADNN---------ENLQEICKAETLVQARKRK 233

  Fly  1228 RRTSFTPQALELLNAHFERNTHPSGTEITGLAHQLGYEREVIRIWFCNKRQALKNT 1283
             |||...:....|...|.:...|:..:|:.:|.|||.|::|:|:||||:||..|.:
Human   234 -RTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRS 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm3	NP_001188885.2	Pou	1108..1200	CDD:304656	28/91 (31%)
		Homeobox	1228..1281	CDD:278475	20/52 (38%)
POU5F1	NP_002692.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		17/70 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..114		7/53 (13%)
		POU	138..212	CDD:197673	29/100 (29%)
		DNA binding. /evidence=ECO:0000250|UniProtKB:P20263	180..186		4/24 (17%)
		DNA binding. /evidence=ECO:0000250|UniProtKB:P20263	193..196		0/2 (0%)
		Homeobox	233..287	CDD:365835	21/54 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810