Protein Alignment pdm3 and POU1F1

DIOPT Version :10

• Sequence 1: NP_001188885.2
• Gene: pdm3 / 35813
• FlyBaseID: FBgn0261588
• Length: 1292
• Species: Drosophila melanogaster
• Sequence 2: NP_001116229.1
• Gene: POU1F1 / 5449
• HGNCID: 9210
• Length: 317
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 108/355 - (30%)
• Similarity: 152/355 - (42%)
• Gaps: 77/355 - (21%)

  Fly   949 SDRGYTSPLFRTHSPQGHALSLGGSPRLERDYLGNGPSSGTATSTSSCGAPTAAGSSATANVLSS 1013
            ||...|.||...||.   |..|              |.|..||:.          .|...::||.
Human    17 SDASATLPLIMHHSA---AECL--------------PVSNHATNV----------MSTVPSILSL 54

  Fly  1014 INRLNASNGELTITKSLGAPTATATRASSASPRDDSPGPGPSTSSVSHMQPLKLSPSSRSEPPH- 1077
            |..........::| :|| .|||....|..|..   .|..|||..|   ....|:|.....|.|
Human    55 IQTPKCLCTHFSVT-TLG-NTATGLHYSVPSCH---YGNQPSTYGV---MAGSLTPCLYKFPDHT 111

  Fly  1078 LSPNGNDNDNDLLMDSPNEPTINQATTN----VVDGIDLD-----EIKEFAKAFKLRRLSLGLTQ 1133
            ||.........||.:.|......|....    |.:.||:|     |:::||..||:||:.||.||
Human   112 LSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQ 176

  Fly  1134 TQVGQALSVTEGPAYSQSAICSSALAAQMYAAQLSTQQQNMFEKLDITPKSAQKIKPVLERWMKE 1198
            |.||:||:...|..:||:.||                   .||.|.::.|:|.|:|.:|.:|::|
Human   177 TNVGEALAAVHGSEFSQTTIC-------------------RFENLQLSFKNACKLKAILSKWLEE 222

  Fly  1199 AEE--SHWNRYKSGQNHLTDYIGVEPSKKRKRRTSFTPQALELLNAHFERNTHPSGTEITGLAHQ 1261
            ||:  :.:|. |.|.|          .:||||||:.:..|.:.|..||.....||..||..:|.:
Human   223 AEQVGALYNE-KVGAN----------ERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEE 276

  Fly  1262 LGYEREVIRIWFCNKRQALKNTVRMMSKGM 1291
            |..|:||:|:||||:||..|.....:::.:
Human   277 LNLEKEVVRVWFCNRRQREKRVKTSLNQSL 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm3	NP_001188885.2	Pou	1108..1200	CDD:473999	34/96 (35%)
		Homeodomain	1226..1282	CDD:459649	25/55 (45%)
POU1F1	NP_001116229.1	POU	150..224	CDD:197673	32/92 (35%)
		Homeodomain	241..297	CDD:459649	25/55 (45%)