Protein Alignment pdm3 and Pou3f1

DIOPT Version :10

• Sequence 1: NP_001188885.2
• Gene: pdm3 / 35813
• FlyBaseID: FBgn0261588
• Length: 1292
• Species: Drosophila melanogaster
• Sequence 2: NP_620193.1
• Gene: Pou3f1 / 192110
• RGDID: 619767
• Length: 451
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 134/543 - (24%)
• Similarity: 180/543 - (33%)
• Gaps: 173/543 - (31%)

  Fly   756 PTGGSPGLAAKGPQPPP----PGAAFLLQQQLHIKP---ETQTHLHHHLQTQSTSAVSSTLPQIS 813
            |.|...|....||...|    ..||....::||...   |.|..:||........
  Rat     9 PRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAG---------- 63

  Fly   814 LRHPDELTAPQMDLKPLELSASTSPPAPPPRHHFGHSLRGSSTVSPKHSPQGRM--GGSGGSTTT 876
              ||..|..||.  .|............|   |..|...|..:.       ||.  ||.||..
  Rat    64 --HPVGLAHPQW--LPTGGGGGGDWAGGP---HLEHGKAGGGST-------GRADDGGGGGGF-- 112

  Fly   877 GMNLSQHHERHDRLERLERQERHERRSHTPTATATRASVSSSSSAGHHGGSLPSGRLSPPSSAPS 941
                      |.||.       |:..:|...|.|       .....||.|         |:.:||
  Rat   113 ----------HARLV-------HQGAAHAGAAWA-------QGGTAHHLG---------PAMSPS 144

  Fly   942 NSAANSISDRGYTSPLFRTHSPQGHALSLGGSPRLERDYLGNGPSSGTATSTSSCGAPTAAGSSA 1006
            ..|...             |.||...|      ..:..|.|.| ..|.|      |...|.|..|
  Rat   145 PGAGGG-------------HQPQPLGL------YAQAAYPGGG-GGGLA------GMLAAGGGGA 183

  Fly  1007 TANVLSSINRLNASNGELTITKSLGAPTATATRASSASPRDDSPGPGPSTSSVSHMQPLKLSPSS 1071
            ...:..:::. :....:|                        .|.|.|...:..|......:...
  Rat   184 GPGLHHALHE-DGHEAQL------------------------EPSPPPHLGAHGHAHGHAHAGGL 223

  Fly  1072 RSEPPHLSPN--------GNDNDNDLLMDSPNEPTINQATTNVVDGIDLDEIKEFAKAFKLRRLS 1128
            .:...||.|.        |..:|.    |:|:.                |::::|||.||.||:.
  Rat   224 HAAAAHLHPGAGGGGSSVGEHSDE----DAPSS----------------DDLEQFAKQFKQRRIK 268

  Fly  1129 LGLTQTQVGQALSVTEGPAYSQSAICSSALAAQMYAAQLSTQQQNMFEKLDITPKSAQKIKPVLE 1193
            ||.||..||.||....|..:||:.||                   .||.|.::.|:..|:||:|.
  Rat   269 LGFTQADVGLALGTLYGNVFSQTTIC-------------------RFEALQLSFKNMCKLKPLLN 314

  Fly  1194 RWMKEAEESHWNRYKSGQNHLTDYIGVEPSKKRKRRTSFTPQALELLNAHFERNTHPSGTEITGL 1258
            :|::|.:.|      ||.....|.|..: .:|||:|||........|.:||.:...||..|||||
  Rat   315 KWLEETDSS------SGSPTNLDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGL 372

  Fly  1259 AHQLGYEREVIRIWFCNKRQALK 1281
            |..|..|:||:|:||||:||..|
  Rat   373 ADSLQLEKEVVRVWFCNRRQKEK 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm3	NP_001188885.2	Pou	1108..1200	CDD:473999	31/91 (34%)
		Homeodomain	1226..1282	CDD:459649	28/56 (50%)
Pou3f1	NP_620193.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		3/11 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..114		13/68 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	134..154		8/41 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..253		12/111 (11%)
		POU	247..321	CDD:197673	33/112 (29%)
		Homeodomain	340..396	CDD:459649	28/56 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	395..451		1/1 (100%)