DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdm3 and Pou4f3

DIOPT Version :9

Sequence 1:	NP_001188885.2	Gene:	pdm3 / 35813	FlyBaseID:	FBgn0261588	Length:	1292	Species:	Drosophila melanogaster
Sequence 2:	NP_620395.2	Gene:	Pou4f3 / 18998	MGIID:	102523	Length:	338	Species:	Mus musculus

Alignment Length:	276	Identity:	76/276 - (27%)
Similarity:	125/276 - (45%)	Gaps:	55/276 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1034 TATATRASSASPRDDSPGPGPSTSSVSHM--QPLK------LSPS---------------SRSEP 1075
            |.::...:|.||......|...||...|.  |.|:      :||:               ::..|
Mouse    82 TMSSVPCTSTSPTVPISHPAALTSHPHHAVHQGLEGDLLEHISPTLSVSGLGAPEHSVMPAQIHP 146

  Fly  1076 PHLSPNGNDNDNDLLMDSPNEPTINQATTNVVDGIDLD--EIKEFAKAFKLRRLSLGLTQTQVGQ 1138
            .||...|:.: ..:.|..|:....:.|....:..::.|  |::.||:.||.||:.||:||..||.
Mouse   147 HHLGAMGHLH-QAMGMSHPHAVAPHSAMPACLSDVESDPRELEAFAERFKQRRIKLGVTQADVGA 210

  Fly  1139 ALSVTEGP---AYSQSAICSSALAAQMYAAQLSTQQQNMFEKLDITPKSAQKIKPVLERWMKEAE 1200
            ||:..:.|   :.|||.||                   .||.|.::..:...:||||:.|::|||
Mouse   211 ALANLKIPGVGSLSQSTIC-------------------RFESLTLSHNNMIALKPVLQAWLEEAE 256

  Fly  1201 ESHWNRYKSGQNHLTDYIGVEPSKKRKRRTSFTPQALELLNAHFERNTHPSGTEITGLAHQLGYE 1265
            .::  |.|:.:..|     ...|:::::|||........|.|:|.....||..:|..:|.:|..:
Mouse   257 AAY--REKNSKPEL-----FNGSERKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLK 314

  Fly  1266 REVIRIWFCNKRQALK 1281
            :.|:|:||||:||..|
Mouse   315 KNVVRVWFCNQRQKQK 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdm3	NP_001188885.2	Pou	1108..1200	CDD:304656	31/96 (32%)
pdm3	NP_001188885.2	Homeobox	1228..1281	CDD:278475	19/52 (37%)
Pou4f3	NP_620395.2	POU-IV box	56..65
		POU	179..256	CDD:197673	31/95 (33%)
		Homeobox	277..331	CDD:395001	20/54 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810