Protein Alignment pdm3 and Pou3f2

DIOPT Version :10

• Sequence 1: NP_001188885.2
• Gene: pdm3 / 35813
• FlyBaseID: FBgn0261588
• Length: 1292
• Species: Drosophila melanogaster
• Sequence 2: NP_032925.1
• Gene: Pou3f2 / 18992
• MGIID: 101895
• Length: 445
• Species: Mus musculus
• Alignment Length: 871
• Identity: 169/871 - (19%)
• Similarity: 220/871 - (25%)
• Gaps: 485/871 - (55%)

  Fly   433 HPHPHHGHQHHHHHPATAAALASLQGLAASVFNSPLNLSVGGEPVATTGPSVAPTSPTHNGGKSK 497
            |..|..|.|.      .|......|.|....:.:   |...|.|::.....:  |:.:|.||
Mouse    20 HAEPPGGMQQ------GAGGYREAQSLVQGDYGA---LQSNGHPLSHAHQWI--TALSHGGG--- 70

  Fly   498 TAKGGSSGNGSGGSSANSGTSSAQQQQQPDNPSSSSSPHHPLSASSLANVLAAATASPPPSLQAP 562
             ..||..|.|.||.....|..|                  |.|.|.|..          |.::
Mouse    71 -GGGGGGGGGGGGGGGGGGDGS------------------PWSTSPLGQ----------PDIK-- 104

  Fly   563 PASAQMPQLILASGQLVQGVQGAQLLIPTAQGIAVQTILTIPVSPQIPTTEQFLPNAFGAFASYQ 627
                  |.:::.     ||.:|.:|..|                              ||.....
Mouse   105 ------PSVVVQ-----QGGRGDELHGP------------------------------GALQQQH 128

  Fly   628 QQQQQQQQQRDLLPPSLAALQHATALPQLAQTPTNLLKPNLFSTGVQQLLTALHPELFAAAAATH 692
            |||||||||
Mouse   129 QQQQQQQQQ-------------------------------------------------------- 137

  Fly   693 QQQQQQQQQQVQQQREREREREREREREREREREQHLGIGHLPHSHLAADLRRSAERS----PTA 753
            ||||||||||.|||                  |..|| :.|..:.|......|||..:    |:.
Mouse   138 QQQQQQQQQQQQQQ------------------RPPHL-VHHAANHHPGPGAWRSAAAAAHLPPSM 183

  Fly   754 GSPTGG----SP-----GLAAKGPQPPPPGAAFLLQQQLHIKPETQTHLHHHLQTQSTSAVSSTL 809
            |:..||    .|     |:...|.||                    ..||||....:...
Mouse   184 GASNGGLLYSQPSFTVNGMLGAGGQP--------------------AGLHHHGLRDAHDE----- 223

  Fly   810 PQISLRHPDELTAPQMDLKPLELSASTSPPAPPPRHHFGHSLRGSSTVSPKHSPQGRMGGSGGST 874
            |..:..||...:.|..           .||.|||                   |||..|..|.
Mouse   224 PHHADHHPHPHSHPHQ-----------QPPPPPP-------------------PQGPPGHPGA-- 256

  Fly   875 TTGMNLSQHHERHDRLERLERQERHERRSHTPTATATRASVSSSSSAGHHGGSLPSGRLSPPSSA 939
                    ||:.|
Mouse   257 --------HHDPH---------------------------------------------------- 261

  Fly   940 PSNSAANSISDRGYTSPLFRTHSPQGHALSLGGSPRLERDYLGNGPSSGTATSTSSCGAPTAAGS 1004
                     ||
Mouse   262 ---------SD------------------------------------------------------ 263

  Fly  1005 SATANVLSSINRLNASNGELTITKSLGAPTATATRASSASPRDDSPGPGPSTSSVSHMQPLKLSP 1069
                                                      :|:|     ||
Mouse   264 ------------------------------------------EDTP-----TS------------ 269

  Fly  1070 SSRSEPPHLSPNGNDNDNDLLMDSPNEPTINQATTNVVDGIDLDEIKEFAKAFKLRRLSLGLTQT 1134
                                                       |::::|||.||.||:.||.||.
Mouse   270 -------------------------------------------DDLEQFAKQFKQRRIKLGFTQA 291

  Fly  1135 QVGQALSVTEGPAYSQSAICSSALAAQMYAAQLSTQQQNMFEKLDITPKSAQKIKPVLERWMKEA 1199
            .||.||....|..:||:.||                   .||.|.::.|:..|:||:|.:|::||
Mouse   292 DVGLALGTLYGNVFSQTTIC-------------------RFEALQLSFKNMCKLKPLLNKWLEEA 337

  Fly  1200 EESHWNRYKSGQNHLTDYIGVEPSKKRKRRTSFTPQALELLNAHFERNTHPSGTEITGLAHQLGY 1264
            :.|      ||.....|.|..: .:|||:|||........|.:||.:...||..|||.||..|..
Mouse   338 DSS------SGSPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQL 395

  Fly  1265 EREVIRIWFCNKRQALKNTVRMMSKG 1290
            |:||:|:||||:||..|   ||...|
Mouse   396 EKEVVRVWFCNRRQKEK---RMTPPG 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm3	NP_001188885.2	Pou	1108..1200	CDD:473999	31/91 (34%)
		Homeodomain	1226..1282	CDD:459649	26/55 (47%)
Pou3f2	NP_032925.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..173		52/258 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..269		28/292 (10%)
		POU	264..338	CDD:197673	35/152 (23%)
		Homeodomain	357..413	CDD:459649	27/58 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	411..445		4/11 (36%)