Protein Alignment pdm3 and pdm3

DIOPT Version :10

• Sequence 1: NP_001188885.2
• Gene: pdm3 / 35813
• FlyBaseID: FBgn0261588
• Length: 1292
• Species: Drosophila melanogaster
• Sequence 2: XP_061509788.1
• Gene: pdm3 / 1280360
• VectorBaseID: AGAMI1_003138
• Length: 871
• Species: Anopheles gambiae
• Alignment Length: 1130
• Identity: 409/1130 - (36%)
• Similarity: 503/1130 - (44%)
• Gaps: 336/1130 - (29%)

  Fly   226 GAAPASPPSASSNSSSH--VLALNIKTES---DFD---KEI-------SCHKIHSPSSSSHAHSL 275
            ||.|      .:|:|||  :|.:::..|.   ||.   ||:       :.|  :..:|......|
Mosquito     5 GADP------ENNNSSHCGMLGISMPCEGAGHDFSTVRKELEYANAIAAAH--YGAASDKGDRIL 61

  Fly   276 HHHHHHHHHPHHSSRSNNNDDEMEITDGHALLSPPPPSHSHSHSPFDSKDHVKELEFYKNLAAKA 340
            .:...:.....|.||||:           ..|:|.|                .:||...:.::|.
Mosquito    62 SYKLENRRRSEHCSRSNS-----------PFLNPTP----------------ADLEGRCSNSSKP 99

  Fly   341 ASLANQHSPPPMPLPLPLPMQIDGEEDENEGEGEGEGEAEEQSAEVMRLRREEQAQAKAFAA--- 402
            ..:....:...|. ||.:|              .|.......:|          |.|.|.||
Mosquito   100 TGILRTVAQDKMS-PLSMP--------------TGPSATSTTAA----------AAAAAVAAAQV 139

  Fly   403 HLNGTMQDMINLQKLQNLATLQQQQQQQQQHPHPHHGHQHHHHHPATAAALASLQGLAAS--VFN 465
            ||||||||||||||||:||.|                        ..|:.|....||..|  :.|
Mosquito   140 HLNGTMQDMINLQKLQSLAQL------------------------TGASVLGPSLGLPTSPLLGN 180

  Fly   466 SPLNLSVGGEPVATTGPSVAPTSPTHNGGKSKTAKGGSSGNGSGGSSANSGTSSAQQQQQPDNPS 530
            ||||||:.|:
Mosquito   181 SPLNLSLSGQ------------------------------------------------------- 190

  Fly   531 SSSSPHHPLSASSLANVLAAATASPPPSLQAPPASAQMPQLILASGQLVQGVQGAQLLIPTAQGI 595
                .|.|       .||....|:|     ...|:.|||||:|||||::||:|||||||||:|||
Mosquito   191 ----NHSP-------QVLGLGPAAP-----IAAAAPQMPQLLLASGQIMQGIQGAQLLIPTSQGI 239

  Fly   596 AVQTILTIPVSPQI---PTTEQFLPNAFGAFASYQQQQQQQQQQRDLLPPSLAALQHATALPQLA 657
            |.||||||||..|:   .::|..|               |.....:.|..:|:: |.|.|....|
Mosquito   240 ATQTILTIPVGQQVISNMSSEALL---------------QSLNFNNSLSETLSS-QAAQAAAAAA 288

  Fly   658 QTPTNLLKPNLFSTGVQQLLTALHPELFAAAAATHQQQQQQQQQQVQQQRERERERERERERERE 722
            .....|..|...:.|.......|..:|..:||..|.||..
Mosquito   289 AASGGLFAPPRDAQGTGSGGGLLSTQLLGSAAGAHAQQHS------------------------- 328

  Fly   723 REREQHLGIGHLPHSHLAADLRRSAERSPTAGSPTGGSPGLAAKGPQPPPPGAAFLLQQQLHIKP 787
             .:..|....|..|.|...|::.....|.|:.|....|..:.:        ||:.:  ..:|
Mosquito   329 -PKGLHYANHHHHHHHHHGDVKFKPNASSTSSSSCSSSSVVVS--------GASCM--SSVH--- 379

  Fly   788 ETQTHLHHHL----QTQSTSAVSSTLPQISLRHPDELTAPQM--DLKPLELSASTSP-------P 839
              .||...||    ...|.||.|:||...|      ..|.:|  |:..::|.|..||       .
Mosquito   380 --DTHRQQHLPPGHSLSSASASSNTLDHRS------AVAGRMTPDMHRVKLQAGDSPKRISLVAS 436

  Fly   840 APPPRHHFGHSLRGSSTVSPKHSPQGRMGGSGGSTTTGMNLSQHHERHDRLERLERQERHERRSH 904
            :||...|    .|.:|..|...||                       :|:...|       :|:.
Mosquito   437 SPPVSTH----SRPASYASCSSSP-----------------------YDKSMTL-------KRAL 467

  Fly   905 TPTATATRASVSSSSSAGHHGGSLPSGRLS-PPSSAPSNSAANSISDRGYTSPLFRTHSPQG--- 965
            :|.||....:.|||||...|..   :|.|. ...||.|.::..|.||   .|.:.|...|.|
Mosquito   468 SPPATLNCTTPSSSSSGSGHSS---NGHLQVNVHSAISAASPRSPSD---ASAINRLGLPTGGVD 526

  Fly   966 -----HALSLGGSPRLERDYLGNGPSSGTATSTS-----SCGAPTAAGSSATANVLSSINRLNAS 1020
                 ..||.|||.........:.|||....|.|     |...|:|.||:.           ...
Mosquito   527 LLPSKSKLSPGGSSSSGLPLTKDQPSSHPHASVSPLHHHSSSGPSAPGSTG-----------RPG 580

  Fly  1021 NGELTITKSLGAPTATATRASSASPRD-DSPGP-GPSTSSVSHMQPLKLSPSSRSEPPHLSPNG- 1082
            :.:|.:.:..........||.||...: :.|.. |.|:.:|..:|......::.:.||.|||.|
Mosquito   581 SCDLELIEQHQHQQQQHHRAPSADDLELEKPSTVGSSSGTVHQLQKRSHHSAASTPPPKLSPAGS 645

  Fly  1083 -------NDNDND-----LLMDSPNEPTINQATTNVVDGIDLDEIKEFAKAFKLRRLSLGLTQTQ 1135
                   :|:|:|     .|.:.|||.||||...|||||||||:|||||||||||||||||||||
Mosquito   646 TGRLSHSDDDDDDASNHEFLEEHPNELTINQTNCNVVDGIDLDDIKEFAKAFKLRRLSLGLTQTQ 710

  Fly  1136 VGQALSVTEGPAYSQSAICSSALAAQMY-AAQLSTQQQNMFEKLDITPKSAQKIKPVLERWMKEA 1199
            ||||||||||||||||||| |||||||| |||||:|||.||||||||||||||||||||||||||
Mosquito   711 VGQALSVTEGPAYSQSAIC-SALAAQMYCAAQLSSQQQQMFEKLDITPKSAQKIKPVLERWMKEA 774

  Fly  1200 EESHWNRYKSGQNHLTDYIGVEPSKKRKRRTSFTPQALELLNAHFERNTHPSGTEITGLAHQLGY 1264
            ||||.:||||||||:.|:||||||||||||||||||||||||.||||||||||||||||||||||
Mosquito   775 EESHSSRYKSGQNHVPDFIGVEPSKKRKRRTSFTPQALELLNGHFERNTHPSGTEITGLAHQLGY 839

  Fly  1265 EREVIRIWFCNKRQALKNTVRMMSK 1289
            |||||||||||||||||||||||||
Mosquito   840 EREVIRIWFCNKRQALKNTVRMMSK 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm3	NP_001188885.2	Pou	1108..1200	CDD:473999	87/92 (95%)
		Homeodomain	1226..1282	CDD:459649	54/55 (98%)
pdm3	XP_061509788.1	None