Protein Alignment pdm3 and pou1f1

DIOPT Version :10

• Sequence 1: NP_001188885.2
• Gene: pdm3 / 35813
• FlyBaseID: FBgn0261588
• Length: 1292
• Species: Drosophila melanogaster
• Sequence 2: XP_031752450.1
• Gene: pou1f1 / 100492413
• XenbaseID: XB-GENE-854097
• Length: 373
• Species: Xenopus tropicalis
• Alignment Length: 659
• Identity: 147/659 - (22%)
• Similarity: 232/659 - (35%)
• Gaps: 221/659 - (33%)

  Fly     5 HVLRDRVWLISGNNGRLLLIATIVALVAGLAEGLGCPQKCSCQ-QRTVRCVKQQLDKVP-EMPPD 67
            |:|   ||:|        |:||...::..     |||..|.|. .:||.|:.::....| .:|||
 Frog     3 HLL---VWII--------LLATAQQMITE-----GCPAGCQCNTPQTVFCLARKNSNFPRSVPPD 51

  Fly    68 TSIIDLRYNHIREVPTGAFDGLQHLHTIFLNENQLTKIHSGAFRDLPSLKYLYLNRNRIGTIAAD 132
            |..:.:..|.|..:...:|.||..||.:.|:.|||:.:..|.||:|.:|..|.|..|::..|:||
 Frog    52 TLNLYVFENGISSIEESSFIGLNGLHLLDLSHNQLSSLPGGVFRNLANLSNLDLTSNQLTEISAD 116

  Fly   133 AFISLSRLHSIYLHGNQIKTIPEGSFERLPSLRRLRLDDNALECDCSLLWFVRTMQQPNRKSLVA 197
            .|..||||..:||:||:|::|...:|:.:.||..|:|.:|.|
 Frog   117 TFQGLSRLERLYLNGNRIRSIHPEAFKGIESLLELKLSNNQL----------------------- 158

  Fly   198 GATCATPPALEGQPISSITEEDFHCAKPEIVVQPRDIEISYG-----QTAVF------SCKASGD 251
                .||||.               :.|.:::    :::||.     |..||      |.:.:|.
 Frog   159 ----VTPPAF---------------SLPHLLL----LDLSYNAIPVIQQGVFNAGNIESLRLAGL 200

  Fly   252 PRPEI-VWLQEGSPIRSE---SDGRITLLPDG----------------SLRIDEIVPADAGQYAC 296
            ...|: ..|..|.....|   ||.::..:|.|                .:::|::....|.|...
 Frog   201 GLKEVPEELLSGLKNLHELDLSDNQLDKVPPGLHGLTKLNIAGNVGFSQIQVDDLSNLPALQELD 265

  Fly   297 IARNSL---------GESRSRTASLAVN------------------------------------- 315
            ::..||         ...|.|..|||.|
 Frog   266 LSGLSLQTLPKGLFRSSKRLRAVSLAQNPFNCVCSLGWLSEWMRVSGVVLLRPDETRCHFPPKNA 330

  Fly   316 ----NEVVESE--AEAPKFLRTPAD-PLELLEGEPIVLDCVVTGAP------TPSILWKFNNENI 367
                .::.:||  ..||..::.|:. |.....|.|.....:.|.||      |.:|..:...|:.
 Frog   331 GKTLRQLRDSEYGCPAPTTIQMPSTMPPSTTTGPPTTTKHLQTEAPTTASTTTTTIPHQEQEEDT 395

  Fly   368 QNGRIKLFGNGSLILPTSTLDDGGIYTCCAGNALGNIS--------------------------- 405
            |..:   |.....:.|..|..:||   .|..:..|.:.
 Frog   396 QPFQ---FDFEDTLCPPQTCLNGG---SCHLDPTGQLECECPPGFQGTYCETGPVTPAVVTEMYI 454

  Fly   406 -----VNVTVLVNAPPRIVLGPENQNVKVGSTLTLECE----ADGNPLPHIWWKKDGLPVNETSQ 461
                 :.|||   :..|:.|...:||.:....:.|...    ||..|:  |:.....||
 Frog   455 EQVKIIEVTV---SSIRVDLQSYSQNKEKLRAIRLTVRNLYGADRRPM--IYKLPPTLP------ 508

  Fly   462 VYFTDDAIELTIDHAEESDSGTYVCVAENELGIAEVEAEVVVINVG-PPRFLFEPYDLDAIEG-- 523
                    |.|: .|..|:|..:||:.....|..|.:.......:| ||:  ..|....:.||
 Frog   509 --------EYTV-RALSSNSSYWVCLGSQGEGGPEEDLCTETHTLGEPPK--HSPQVTQSQEGNL 562

  Fly   524 TTVEMPCKA 532
            |.|.:|..|
 Frog   563 TLVLVPAVA 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm3	NP_001188885.2	Pou	1108..1200	CDD:473999
		Homeodomain	1226..1282	CDD:459649
pou1f1	XP_031752450.1	POU	205..279	CDD:197673	12/73 (16%)
		Homeodomain	296..352	CDD:459649	4/55 (7%)