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Protein Alignment CG30371 and C1S

DIOPT Version :9

Sequence 1:	NP_610370.1	Gene:	CG30371 / 35806	FlyBaseID:	FBgn0050371	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001725.1	Gene:	C1S / 716	HGNCID:	1247	Length:	688	Species:	Homo sapiens

Alignment Length:	381	Identity:	88/381 - (23%)
Similarity:	140/381 - (36%)	Gaps:	122/381 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 VQCSLGIPKG--NGQ----------------CTTDNFWLDTEGDLLMRGAENFC-GSGTLSRESL 111
            |.|  |||:.  ||:                |....::::..|     |.|..| |:|:...|.|
Human   357 VDC--GIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGG-----GGEYHCAGNGSWVNEVL 414

  Fly   112 FTELVFAYISTGTKGGSFKCTLTTVKQNCNCG-----WSATTRIANGQQAAANEFPSMAALKDVT 171
            ..||.             ||...       ||     :....||..|..|....||......:
Human   415 GPELP-------------KCVPV-------CGVPREPFEEKQRIIGGSDADIKNFPWQVFFDN-- 457

  Fly   172 KNQASFCGGTIVAHRYILTAAHCIYQVSRATNIVAIVGTNDLGNPSSSRYYQQYNIQ-------Q 229
                .:.||.::...::|||||.:.                 ||...:.|....::|       :
Human   458 ----PWAGGALINEYWVLTAAHVVE-----------------GNREPTMYVGSTSVQTSRLAKSK 501

  Fly   230 MIPHEQYVSDP------------DVNNDIAVLITASNIQWSRGVGPICLPPVGTSTPFTYDLVD- 281
            |:..|.....|            :.:||||::.....::....|.|||||  |||:  .|:|:|
Human   502 MLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLP--GTSS--DYNLMDG 562

  Fly   282 ----VIGYGTVFFAGPTSTSLQKINLNVVTNQDC------QTEYNNVATIYTGQM-CTYDYSG-T 334
                :.|:|.. .....:..|:...|.|...:.|      :...:..|.::|..| |.   .| .
Human   563 DLGLISGWGRT-EKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICA---GGEK 623

  Fly   335 GRDSCQFDSGGPVILR----KSRQFLVGIISYGKSCAESQYPMGVNTRITSYISWI 386
            |.|||:.||||...::    |::.:..|::|:|..|.    ..|:.||:.:|:.||
Human   624 GMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG----TYGLYTRVKNYVDWI 675

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.