DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30371 and Masp2

DIOPT Version :9

Sequence 1:	NP_610370.1	Gene:	CG30371 / 35806	FlyBaseID:	FBgn0050371	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_742040.1	Gene:	Masp2 / 64459	RGDID:	620214	Length:	685	Species:	Rattus norvegicus

Alignment Length:	376	Identity:	100/376 - (26%)
Similarity:	157/376 - (41%)	Gaps:	86/376 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 PNNYPGGTSCRYKFTAPLDY-----------YIQVQC--SLGIPKGNGQ--CTTDNFWLDTEGDL 92
            |::.|.|         .:||           .||..|  :......||:  |..|.||..::|:.
  Rat   369 PDDLPNG---------HVDYITGPEVTTYKAVIQYSCEETFYTMSSNGKYVCEADGFWTSSKGEK 424

  Fly    93 LMRGAENFCGSGTLSRESLFTELVFAYISTGTKGGSFKCTLTTVKQNCNCGWSATTRIANGQQAA 157
            .:...:..||                 :||.|.||                     ||..||.|.
  Rat   425 SLPVCKPVCG-----------------LSTHTSGG---------------------RIIGGQPAK 451

  Fly   158 ANEFPSMAALKDVTKNQASFCGGTIVAHRYILTAAHCIYQVSRATNIVAI-VGTNDLGNPSSSRY 221
            ..:||....|...|.     ..|.::...::|||||.:|..:.|.:.:.| :|.....:|    :
  Rat   452 PGDFPWQVLLLGETT-----AAGALIHDDWVLTAAHAVYGKTEAMSSLDIRMGILKRLSP----H 507

  Fly   222 YQQYNIQQMIPHEQYVSDPDVNNDIAVLITASNIQWSRGVGPICLPPVGTSTPFTYDLV-DVIGY 285
            |.|...:.:..||.|......:||||::...:.:..:|.:.|||||....::....|.| .|.|:
  Rat   508 YTQAWPEAVFIHEGYTHGAGFDNDIALIKLKNKVTINRNIMPICLPRKEAASLMKTDFVGTVAGW 572

  Fly   286 GTVFFAGPTSTSLQKINLNVVTNQDCQTEYNNV----ATIYTGQMCTYDYSGTGRDSCQFDSGGP 346
            | :...|..:.:|..:::.:|.:|.|.|.|...    |.:....:|....:| |:|||:.||||.
  Rat   573 G-LTQKGFLARNLMFVDIPIVDHQKCATAYTKQPYPGAKVTVNMLCAGLDAG-GKDSCRGDSGGA 635

  Fly   347 VIL---RKSRQFLVGIISYGK-SCAES-QYPMGVNTRITSYISWIRQKIGN 392
            ::.   ...|.|:.||:|:|. :|..| ||  ||.|::|:||.||...|.|
  Rat   636 LVFLDNETQRWFVGGIVSWGSINCGGSEQY--GVYTKVTNYIPWIENIINN 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30371	NP_610370.1	CUB	24..>67	CDD:294042	7/34 (21%)
		Tryp_SPc	149..386	CDD:214473	74/247 (30%)
		Tryp_SPc	150..389	CDD:238113	75/249 (30%)
Masp2	NP_742040.1	CUB	19..136	CDD:238001
		FXa_inhibition	152..180	CDD:291342
		CUB	184..295	CDD:238001
		Sushi	300..361	CDD:278512
		Sushi	366..429	CDD:278512	15/68 (22%)
		Tryp_SPc	443..678	CDD:214473	74/247 (30%)
		Tryp_SPc	444..681	CDD:238113	75/249 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000