DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30371 and C1s1

DIOPT Version :9

Sequence 1:NP_610370.1 Gene:CG30371 / 35806 FlyBaseID:FBgn0050371 Length:399 Species:Drosophila melanogaster
Sequence 2:NP_001091086.1 Gene:C1s1 / 50908 MGIID:1355312 Length:694 Species:Mus musculus


Alignment Length:480 Identity:102/480 - (21%)
Similarity:164/480 - (34%) Gaps:145/480 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 EGCDNTFNLSPGTTYVE-----SPYYPNNYPG--------------------------------- 48
            |..|:..|.....|:..     .||..|.:||                                 
Mouse   232 EPADSEGNCPDSLTFASKNQQFGPYCGNGFPGPLTIRTQSNTLGIVFQTDLMGQKKGWKLRYHGD 296

  Fly    49 GTSCRYKFTAPLDY-----------YIQVQCSLGIPKGNGQ---------CTTDNFWLDTEGDLL 93
            ..||..|.||...:           .:::.|..|.....|.         |.:|..|.::.    
Mouse   297 PISCAKKITANSTWQPDKAKYVFKDVVKITCVDGFEVVEGHVSSTSYYSTCQSDGQWSNSG---- 357

  Fly    94 MRGAENFCG------SGTLS--RESLFTELVF------AYISTGTKGGSFKCT---------LTT 135
            ::....:||      :|.:.  ..|:|..:|.      .|.....:||.::|.         |..
Mouse   358 LKCQPVYCGIPDPIANGKVEEPENSVFGTVVHYTCEEPYYYMEHEEGGEYRCAANGRWVNDQLGI 422

  Fly   136 VKQNC--NCG-----WSATTRIANGQQAAANEFPSMAALKDVTKNQASF----CGGTIVAHRYIL 189
            ....|  .||     :....||..||.|....||.          |..|    ..|.::...::|
Mouse   423 ELPRCIPACGVPTEPFQVHQRIFGGQPAKIENFPW----------QVFFNHPRASGALINEYWVL 477

  Fly   190 TAAHCIYQVSRATNIVAIVGTNDLGNPSSSRYYQQYNIQQMIPHEQYVSDPDVN------NDIAV 248
            ||||.:.::|.....|..:........::.|.|.    :::..|..:..:.|.|      ||||:
Mouse   478 TAAHVLEKISDPLMYVGTMSVRTTLLENAQRLYS----KRVFIHPSWKKEDDPNTRTNFDNDIAL 538

  Fly   249 LITASNIQWSRGVGPICLPPVGTSTPFTYDLVDVIGYGTVFFAGPTSTSLQKINLN-----VVTN 308
            :.....::....|.|||||  |||:.:.....|:   |.:...|.|...:..|||.     |.:.
Mouse   539 VQLKDPVKMGPKVSPICLP--GTSSEYNVSPGDM---GLISGWGSTEKKVFVINLRGAKVPVTSL 598

  Fly   309 QDC-QTEYNNVAT-----IYTGQM-CTYDYSGTGRDSCQFDSGGPVILR-----KSRQFLVGIIS 361
            :.| |.:..|...     ::|..| |..:   .|.|||..||||....:     ..:.::.|::|
Mouse   599 ETCKQVKEENPTVRPEDYVFTDNMICAGE---KGVDSCHGDSGGAFAFQVPNVTVPKFYVAGLVS 660

  Fly   362 YGKSCAESQYPMGVNTRITSYISWI 386
            :||.|.    ..||.|::.:|:.||
Mouse   661 WGKRCG----TYGVYTKVKNYVDWI 681

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30371NP_610370.1 CUB 24..>67 CDD:294042 13/91 (14%)
Tryp_SPc 149..386 CDD:214473 66/263 (25%)
Tryp_SPc 150..389 CDD:238113 67/264 (25%)
C1s1NP_001091086.1 CUB 24..135 CDD:238001
FXa_inhibition 149..177 CDD:373209
CUB 181..293 CDD:366096 9/60 (15%)
CCP 307..361 CDD:153056 6/57 (11%)
CCP 365..428 CDD:153056 11/62 (18%)
Tryp_SPc 443..681 CDD:214473 66/263 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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