DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30371 and TMPRSS7

DIOPT Version :9

Sequence 1:NP_610370.1 Gene:CG30371 / 35806 FlyBaseID:FBgn0050371 Length:399 Species:Drosophila melanogaster
Sequence 2:NP_001382436.1 Gene:TMPRSS7 / 344805 HGNCID:30846 Length:843 Species:Homo sapiens


Alignment Length:511 Identity:114/511 - (22%)
Similarity:192/511 - (37%) Gaps:161/511 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 VLAYFE-----GCDNTFNLSPGTTY---VESPYYPNNYPGGTSCRYKFTAPLD------------ 61
            :.||||     .|:||..:...|.:   :.|||||:.||....|.:||...|.            
Human   353 IRAYFEVIPEQKCENTVLVKDITGFEGKISSPYYPSYYPPKCKCTWKFQTSLSTLGIALKFYNYS 417

  Fly    62 --------------------------------------YYIQVQCSLGI---------------- 72
                                                  .:||:|||..:                
Human   418 ITKKSMKGCEHGWWEINEHMYCGSYMDHQTIFRVPSPLVHIQLQCSSRLSDKPLLAEYGSYNISQ 482

  Fly    73 --PKGNGQCTTD------------NFWLDTEGDLLMRGAENFCGSGTLSR--------------- 108
              |.|:.:|::.            |...|...:|.....:..|.:.:..:               
Human   483 PCPVGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVSPQPACNTSSFRQHGPLICDGFRDCENG 547

  Fly   109 --ESLFTELVFAYISTGTKGGSFKC--TLTTVKQN-----------------CNCGWSATT--RI 150
              |...|:      |......:|||  .:...|||                 |.|..|::.  ||
Human   548 RDEQNCTQ------SIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEEGCTCSRSSSALHRI 606

  Fly   151 ANGQQAAANEFPSMAALKDVTKNQASFCGGTIVAHRYILTAAHCIY--QVSRATNIVAIVGTNDL 213
            ..|.......:|...:|..|   .:::||.::::..::|:||||.:  ::|..|...|.:|....
Human   607 IGGTDTLEGGWPWQVSLHFV---GSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQ 668

  Fly   214 GNPSSSRYYQQYNIQQMIPHEQYVSDPDVNNDIAVLITASNIQW----SRGVGPICLPPVGTSTP 274
            ||   :::...  :::::.||.|.|. ..:.|||:|  ..:|.|    .:.:.|||:||.|....
Human   669 GN---AKFVSP--VRRIVVHEYYNSQ-TFDYDIALL--QLSIAWPETLKQLIQPICIPPTGQRVR 725

  Fly   275 FTYDLVDVIGYGTVFFA-GPTSTSLQKINLNVVTNQDCQTEYNNVATIYTGQM-CTYDYSGTGRD 337
             :.:...|.|:|....| ...|..||:..:.::....|.:.|.    |.|.:| |....||. ||
Human   726 -SGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTYG----IITSRMLCAGIMSGK-RD 784

  Fly   338 SCQFDSGGPVILRK---SRQFLVGIISYGKSCAESQYPMGVNTRITSYISWIRQKI 390
            :|:.|||||:..|:   .:..|.||:|:|.......:| ||.||:::::.||.:.:
Human   785 ACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFP-GVYTRVSNFVPWIHKYV 839

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30371NP_610370.1 CUB 24..>67 CDD:294042 17/95 (18%)
Tryp_SPc 149..386 CDD:214473 69/247 (28%)
Tryp_SPc 150..389 CDD:238113 70/249 (28%)
TMPRSS7NP_001382436.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 27..67
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 148 1.000 Inparanoid score I4403
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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