DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30371 and gd

DIOPT Version :9

Sequence 1:	NP_610370.1	Gene:	CG30371 / 35806	FlyBaseID:	FBgn0050371	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001259479.1	Gene:	gd / 32159	FlyBaseID:	FBgn0000808	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	91/468 - (19%)
Similarity:	160/468 - (34%)	Gaps:	162/468 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LRHLPLI----SLLLFAPTVLAYFEGCDNTFNLSPGTTYVESPYYPNNYPGGTSCRYKFTAPLDY 62
            :|.|..|    |.||..|..    |....|.:..|.|.:::....|........|. :....||:
  Fly   138 IRKLSFIPDKKSSLLLDPEE----EEVRKTDDKPPSTPHIQFKKKPFAQAPKEICG-RIDRDLDF 197

  Fly    63 YI-----QVQCSLGIPKGNGQCTTDNFWLDTEGDLLMRGAENFCGSGTLSRESLFTELVFAYIST 122
            ::     .:..::|.||.:...|:..|..|.|.|:|               |..|.:
  Fly   198 HLSQRTESLHVAIGEPKSSDGITSPVFVDDDEDDVL---------------EHQFVD-------- 239

  Fly   123 GTKGGSFKCTLTTVKQNCNCGWSATTRIANGQQAAANEFPSMAALKDVTKNQASF---CGGTIVA 184
                   :.....::.:......:.||         ..:|.:||:  ...|..|.   |||::|:
  Fly   240 -------ESEAEAIESDSADSLPSITR---------GSWPWLAAI--YVNNLTSLDFQCGGSLVS 286

  Fly   185 HRYILTAAHCIYQVSR---ATNIVAIVGTNDLGNPSSSRYYQQYNIQQMI--PHEQYVSDPDVNN 244
            .|.::::|||....::   :..::..:|.::|.|         :|.:..:  |.:.....||.|:
  Fly   287 ARVVISSAHCFKLFNKRYTSNEVLVFLGRHNLKN---------WNEEGSLAAPVDGIYIHPDFNS 342

  Fly   245 -------DIAVLITASNIQWSRGVGPICLPPVGTSTPFTYDLVD----VIGYGTVFFAGPTSTSL 298
                   ||||:|....::::..:.|.||....:.|.:   :|.    |||:.   |.....|..
  Fly   343 QLSSYDADIAVIILKDEVRFNTFIRPACLWSGSSKTEY---IVGERGIVIGWS---FDRTNRTRD 401

  Fly   299 QKINLN------------------VVTNQDC--------------------QTE----YNNVATI 321
            ||::..                  :|.|.:|                    |.|    :.:.|:|
  Fly   402 QKLSSELPGKKSTDASAPKVVKAPIVGNAECFRANAHFRSLSSNRTFCAGIQAEERDTHQSGASI 466

  Fly   322 YTGQMCTYDYSGTGRDSCQFDSGGPVILRKSRQFLVGIISYG-------------KSCAESQYPM 373
            |||      .||.|.          .|.|.:|..|.|.:|..             |.|.::||.
  Fly   467 YTG------ISGAGL----------FIRRNNRWMLRGTVSAALPAVETPDAESSHKLCCKNQYI- 514

  Fly   374 GVNTRITSYISWI 386
             :...:..::.||
  Fly   515 -IYADVAKFLDWI 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30371	NP_610370.1	CUB	24..>67	CDD:294042	7/47 (15%)
		Tryp_SPc	149..386	CDD:214473	62/310 (20%)
		Tryp_SPc	150..389	CDD:238113	63/311 (20%)
gd	NP_001259479.1	GD_N	27..124	CDD:292649
		Tryp_SPc	257..526	CDD:238113	63/312 (20%)
		Tryp_SPc	258..526	CDD:214473	63/311 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456035
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030