Protein Alignment CG14760 and C1S

DIOPT Version :9

• Sequence 1: NP_610366.1
• Gene: CG14760 / 35802
• FlyBaseID: FBgn0033277
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001725.1
• Gene: C1S / 716
• HGNCID: 1247
• Length: 688
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 124/568 - (21%)
• Similarity: 194/568 - (34%)
• Gaps: 168/568 - (29%)

  Fly    37 INSPYYPALYPVGTSCRYAVEAPKDHVLQFKCELQLRTLSTDLKCRTEVFHFNSEGDEVLTSSEY 101
            |.||.||..||..:.|.|.:...|.    |:..:.||....|::..      :|.|: .|.|..:
Human   187 IASPNYPKPYPENSRCEYQIRLEKG----FQVVVTLRREDFDVEAA------DSAGN-CLDSLVF 240

  Fly   102 ---------FCGSG-----KFERKSFLNRAVISYISSGHSEPPSAVKLKDKLHAVPTTSTTTEAP 152
                     :||.|     ..|.||.....:.....:|..:     ..|.:.|..|......:.|
Human   241 VAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKK-----GWKLRYHGDPMPCPKEDTP 300

  Fly   153 QAVSIEEQDAEEEQEEEEEPEEADEDLSDEVLHVLQDVGVSDALAYVASLLYDVEESRKSSTTIY 217
            .:|              .||.:|.        :|.:||.....|..     ::|.|.|..:|:.|
Human   301 NSV--------------WEPAKAK--------YVFRDVVQITCLDG-----FEVVEGRVGATSFY 338

  Fly   218 -------------LDKLPIRSSSKTSAKRARI----------VSSYPTAAP---SPGHGGGRFSC 256
                         |...|:......|.:..::          |..|....|   ....|||.:.|
Human   339 STCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHC 403

  Fly   257 ---------LVEAFQPTC--SCGWSRIP-----RIASPTNEEAVLHEFPPMAGVLTKKHGKVF-- 303
                     ::....|.|  .||..|.|     ||..  ..:|.:..||          .:||
Human   404 AGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIG--GSDADIKNFP----------WQVFFD 456

  Fly   304 ---CGAAIIHHRYLLSAAHCFLG------------PETNSAAKLRVVVGEHDLASSFETFATQRY 353
               .|.|:|:..::|:|||...|            .:|:..||.:::..||
Human   457 NPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEH-------------- 507

  Fly   354 DLDALILHE-----DFSQASGQPKNDIAMLKTRMAIVWSQHVGPACLPLQPGEDGQKLPLAGHQV 413
                :.:|.     :..:......||||:::.:..:.....|.|.||   ||.......:.|...
Human   508 ----VFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICL---PGTSSDYNLMDGDLG 565

  Fly   414 VAAGWGTTSYGGPQTHRLLKATLDVIDGRRCRQ-------ALSSAGGLPPHTFCT-YTPGRDTCQ 470
            :.:|||.|. ...:..||..|.|.|...|:|::       |.:.|....|:..|. ...|.|:|:
Human   566 LISGWGRTE-KRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCK 629

  Fly   471 YDSGGALY---ERINGRLMAVGIVSFGQACAAQQPSVNTRVASFIKWI 515
            .|||||..   .....:..|.|:||:|..|...  .:.|||.:::.||
Human   630 GDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTY--GLYTRVKNYVDWI 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14760	NP_610366.1	CUB	37..126	CDD:294042	24/102 (24%)
		Tryp_SPc	281..516	CDD:238113	64/268 (24%)
		Tryp_SPc	281..515	CDD:214473	62/266 (23%)
C1S	NP_001725.1	CUB	18..129	CDD:238001
		FXa_inhibition	143..171	CDD:405372
		CUB	175..287	CDD:395345	26/115 (23%)
		CCP	294..355	CDD:153056	15/87 (17%)
		Sushi	359..421	CDD:395037	9/61 (15%)
		Tryp_SPc	438..678	CDD:238113	65/274 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000