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Protein Alignment CG14760 and ST14

DIOPT Version :9

Sequence 1:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_068813.1	Gene:	ST14 / 6768	HGNCID:	11344	Length:	855	Species:	Homo sapiens

Alignment Length:	577	Identity:	143/577 - (24%)
Similarity:	220/577 - (38%)	Gaps:	124/577 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FLPLLKASSTNAIFEQCNHQVKLQSGQKLLINSPYYPALYPVGTSCRYAVEAPKD-HVLQFKCEL 70
            |..|.:.||       |..:::...|   ..||||||..||....|.:.:|.|.: ||
Human   331 FFQLPRMSS-------CGGRLRKAQG---TFNSPYYPGHYPPNIDCTWNIEVPNNQHV------- 378

  Fly    71 QLRTLSTDLKCRTEVFHFNSEG--------DEVLTSSEYFCGSGKFERKSFLNRAVISYISSGHS 127
                     |.|.:.|:....|        |.|..:.|.:||    ||..|:       ::|..:
Human   379 ---------KVRFKFFYLLEPGVPAGTCPKDYVEINGEKYCG----ERSQFV-------VTSNSN 423

  Fly   128 EPPSAVKLKDKLHAVPTTSTTTEAPQAVSIEEQDAEEEQ----------EEEEEPEEAD-EDLSD 181
                  |:..:.|:..:.:.|....:.:|.:..|....|          :|......|| .|.||
Human   424 ------KITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSD 482

  Fly   182 EVLHVLQDVG--------VSDALAYVASLLYDVEESR------------KSSTTIYLDKLPI--- 223
            | |:...|.|        ....|.:|...:.|..::.            :.|....|.|...
Human   483 E-LNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQCNG 546

  Fly   224 -----RSSSKTSAKRARIVS----SYPT---AAPSPGHG--GGRFSCLVEAFQPTCSCG---WSR 271
                 ..|.:.|..:..:|:    :|..   ...|.|:.  .|:..|...:.:..|.||   ::|
Human   547 KDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEKDCDCGLRSFTR 611

  Fly   272 IPRIASPTNEEAVLHEFPPMAGVLTKKHGKVFCGAAIIHHRYLLSAAHCFL---GPETNSAAKLR 333
            ..|:...|:.:.  .|:|....:.....|.: |||::|...:|:|||||::   |...:...:..
Human   612 QARVVGGTDADE--GEWPWQVSLHALGQGHI-CGASLISPNWLVSAAHCYIDDRGFRYSDPTQWT 673

  Fly   334 VVVGEHDLASSFETFATQRYDLDALILHEDFSQASGQPKNDIAMLKTRMAIVWSQHVGPACLPLQ 398
            ..:|.|| .|.......|...|..:|.|..|:..:..  .|||:|:......:|..|.|.|||
Human   674 AFLGLHD-QSQRSAPGVQERRLKRIISHPFFNDFTFD--YDIALLELEKPAEYSSMVRPICLP-- 733

  Fly   399 PGEDGQKLPLAGHQVVAAGWGTTSYGGPQTHRLLKATLDVIDGRRCRQALSSAGGLPPHTFCT-- 461
               |...:..||..:...|||.|.|||.....|.|..:.||:...|...|...  :.|...|.
Human   734 ---DASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLLPQQ--ITPRMMCVGF 793

  Fly   462 YTPGRDTCQYDSGGALYE-RINGRLMAVGIVSFGQACAAQ-QPSVNTRVASFIKWIR 516
            .:.|.|:||.||||.|.. ..:||:...|:||:|..||.: :|.|.||:..|..||:
Human   794 LSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIK 850

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.