Protein Alignment CG14760 and Masp1

DIOPT Version :9

• Sequence 1: NP_610366.1
• Gene: CG14760 / 35802
• FlyBaseID: FBgn0033277
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: XP_006248588.1
• Gene: Masp1 / 64023
• RGDID: 620213
• Length: 733
• Species: Rattus norvegicus
• Alignment Length: 588
• Identity: 128/588 - (21%)
• Similarity: 226/588 - (38%)
• Gaps: 182/588 - (30%)

  Fly    37 INSPYYPALYPVGTSCRYAVEAPKDHV--LQFKCELQLRTLSTDLKCRTEVFHFNSEGDEVLTSS 99
            |.||.||..||..:.|.|.::..:..:  |||:                ::|.. .:..||....
  Rat   202 ITSPDYPNPYPKSSECSYTIDLEEGFMVTLQFE----------------DIFDI-EDHPEVPCPY 249

  Fly   100 EY------------FCGSGKFERKSFLNRAV----------------ISYISSGHSEPPSAVKLK 136
            :|            |||....|..|..:.::                :||.::|:..|    ||:
  Rat   250 DYIKIKAGSKVWGPFCGEKSPEPISTQSHSIQILFRSDNSGENRGWRLSYRAAGNECP----KLQ 310

  Fly   137 DKLHAVPTTSTTTEAPQAVSIEEQDAEEEQEEEEEPEEADEDLSDEVL-------HVLQDVGVSD 194
            ..::.                           :.||.:|.....|:||       .||:|..|.|
  Rat   311 PPVYG---------------------------KIEPSQAVYSFKDQVLISCDTGYKVLKDNEVMD 348

  Fly   195 ALAYVASLLYDVEESRKSSTTIYLD-KLP--IRSSSKTSAKRARIVSSYPTAAPSPGHGGGRFSC 256
              .:....|.|...|.|..|...:| .:|  ::....|.:.|..: ::|.:..        |:||
  Rat   349 --TFQIECLKDGAWSNKIPTCKIVDCGVPAVLKHGLVTFSTRNNL-TTYKSEI--------RYSC 402

  Fly   257 --------------------------LVEAFQPTC--SCGW-SR-----IPRIASPTNEEAVLHE 287
                                      :::...|||  .||. ||     :.||....|.|..|
  Rat   403 QQPYYKMLHNTTGVYTCSAHGTWTNEVLKRSLPTCLPVCGQPSRALPNLVKRIIGGRNAELGL-- 465

  Fly   288 FPPMAGVLTKKHGKV-----FCGAAIIHHRYLLSAAHCFLGPETN------SAAKLRVVVGEHDL 341
            ||..|.::.:...::     |...|::...::|:|||.......:      |...:.|.:|.||:
  Rat   466 FPWQALIVVEDTSRIPNDKWFGSGALLSESWILTAAHVLRSQRRDNTVIPVSKDHVTVYLGLHDV 530

  Fly   342 ---ASSFETFATQRYDLDALILHEDFSQASGQPKNDIAMLKTRMAIVWSQHVGPACLPLQPGEDG 403
               :.:..:.|.:      ::||.||:..:  ..:|||:::.:..:....||.|.||| :|..:|
  Rat   531 RDKSGAVNSSAAR------VVLHPDFNIQN--YNHDIALVQLQEPVPLGAHVMPICLP-RPEPEG 586

  Fly   404 QKLPLAGHQVVAAGWGTTSYGGPQTHRLLKAT-----------LDVIDGRRCRQALSSAGG---L 454
            ....:.|   :.||||.::........::..|           |.|:....|:.:..|..|   :
  Rat   587 PAPHMLG---LVAGWGISNPNVTVDEIIISGTRTLSDVLQYVKLPVVSHAECKASYESRSGNYSV 648

  Fly   455 PPHTFCT--YTPGRDTCQYDSGGA--LYERINGRLMAVGIVSFG--QACAAQQP-SVNTRVASFI 512
            ..:.||.  |..|:|||..|||||  :::.::.|.:|.|:||:|  :.|.::|. .|.|:|::::
  Rat   649 TENMFCAGYYEGGKDTCLGDSGGAFVIFDEMSQRWVAQGLVSWGGPEECGSKQVYGVYTKVSNYV 713

  Fly   513 KWI 515
            .|:
  Rat   714 DWL 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14760	NP_610366.1	CUB	37..126	CDD:294042	23/118 (19%)
		Tryp_SPc	281..516	CDD:238113	67/270 (25%)
		Tryp_SPc	281..515	CDD:214473	66/268 (25%)
Masp1	XP_006248588.1	CUB	33..142	CDD:238001
		FXa_inhibition	158..186	CDD:291342
		CUB	190..299	CDD:278839	21/113 (19%)
		CCP	306..368	CDD:153056	19/94 (20%)
		CCP	372..437	CDD:153056	8/73 (11%)
		Tryp_SPc	454..715	CDD:214473	69/274 (25%)
		Tryp_SPc	455..716	CDD:238113	68/274 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000