DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14760 and CG10041

DIOPT Version :9

Sequence 1:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_650177.2	Gene:	CG10041 / 41496	FlyBaseID:	FBgn0038014	Length:	287	Species:	Drosophila melanogaster

Alignment Length:	306	Identity:	71/306 - (23%)
Similarity:	107/306 - (34%)	Gaps:	82/306 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 FQPTCSCGWSRIPRIASPTNEEAVLHEFPPMA---------------------GVLTKKHGKVFC 304
            :|..||..|......|..|..:...:..|.:|                     |...|.:.|..|
  Fly     4 WQSLCSIAWFAAMSAAQETLSDTPQNSTPLLATTVSTTKVISFRPRYPYIVSIGENLKGYYKHLC 68

  Fly   305 GAAIIHHRYLLSAAHCFLGPETNSAAKLRVVVGEHDLASSFET--FATQRYDLDALILHEDFSQA 367
            ...|:.:.::||||||.   :||...:|.|..|...|.|..:|  |..:|.      .|..|...
  Fly    69 VGVILSNEFVLSAAHCI---QTNPTKQLYVAGGADSLNSRKQTRFFVVERR------WHPQFRVL 124

  Fly   368 SGQPKNDIAMLKTRMAIVWSQHVGPACLPLQPGED---------GQKLPLAGHQVVAAGWGTTSY 423
            .|   ||||:|:              ..|..|.:|         |:....:|.|....|||....
  Fly   125 GG---NDIAVLR--------------IYPKFPLDDVRFRSINFAGKPQRDSGTQASLVGWGRVGV 172

  Fly   424 GGPQTHRLLKATLDVIDGRRCRQALSSAGGLPPHTFCTYTP----------GRDTCQYDSGGALY 478
            |  :..:|.:.....::...|:|:         |.|....|          .|..|..|||..|.
  Fly   173 G--KIRKLQEMPFLTMENDECQQS---------HRFVFLKPLDICAMHLKGPRGPCDGDSGAPLM 226

  Fly   479 ERINGRLMAVGIVSFG-QACAAQQPSVNTRVASFIKWIRTKSPEVA 523
            .....:|  .|::|:| :||...:|...||:.::..||:.....:|
  Fly   227 NVAKEKL--YGLLSYGRKACTPLKPYAFTRINAYSSWIQESMDSMA 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14760	NP_610366.1	CUB	37..126	CDD:294042
		Tryp_SPc	281..516	CDD:238113	63/277 (23%)
		Tryp_SPc	281..515	CDD:214473	62/276 (22%)
CG10041	NP_650177.2	Tryp_SPc	49..264	CDD:238113	62/253 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456016
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030