DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14760 and CG16749

DIOPT Version :9

Sequence 1:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_649881.1	Gene:	CG16749 / 41111	FlyBaseID:	FBgn0037678	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	263	Identity:	72/263 - (27%)
Similarity:	108/263 - (41%)	Gaps:	37/263 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 SCGWSRIPRIASPTNEEAVLHEFP-PMAGVLTKKHGKVFCGAAIIHHRYLLSAAHCFLGPETNSA 329
            |.|..::.|:.:.|:.....:.|. .|.|    ..|...||.:||..:::::||||..|   ..|
  Fly    21 SHGAPQMGRVVNGTDSSVEKYPFVISMRG----SSGSHSCGGSIISKQFVMTAAHCTDG---RKA 78

  Fly   330 AKLRVVVGEHDLASSFETFATQRYDLDALILHEDFSQASGQPKNDIAMLKTRMAIVW-SQHVGPA 393
            :.|.|..|    .:...........:..:|.|||::..:.. .|||::|.......: ...|.|.
  Fly    79 SDLSVQYG----VTKINATGPNVVRVKKIIQHEDYNPYNNY-ANDISLLLVEEPFEFDGVTVAPV 138

  Fly   394 CLP----LQPGEDGQKLPLAGHQVVAAGWGTTSYGGPQTHRLLKATLDVIDGRRCRQALSSAGGL 454
            .||    ..|..|      ||.:.|..|||..:.||.....|.:..|.|.....|.:   ..||.
  Fly   139 KLPELAFATPQTD------AGGEGVLIGWGLNATGGYIQSTLQEVELKVYSDEECTE---RHGGR 194

  Fly   455 --PPHTFC--TYTPGRDTCQYDSGGALYERINGRLMAVGIVSFG-QAC-AAQQPSVNTRVASFIK 513
              |.:..|  ....|:..|..||||.|.  .||:  .|||||:. :.| .|..|.|..:|:.::.
  Fly   195 TDPRYHICGGVDEGGKGQCSGDSGGPLI--YNGQ--QVGIVSWSIKPCTVAPYPGVYCKVSQYVD 255

  Fly   514 WIR 516
            ||:
  Fly   256 WIK 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14760	NP_610366.1	CUB	37..126	CDD:294042
		Tryp_SPc	281..516	CDD:238113	67/246 (27%)
		Tryp_SPc	281..515	CDD:214473	66/245 (27%)
CG16749	NP_649881.1	Tryp_SPc	29..257	CDD:214473	68/252 (27%)
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	69/254 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456014
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930