DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14760 and CG12951

DIOPT Version :9

Sequence 1:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	257	Identity:	69/257 - (26%)
Similarity:	103/257 - (40%)	Gaps:	35/257 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 IPRIASPTNEEAVLHEFPPMAGVLTKKHGKVFCGAAIIHHRYLLSAAHCFLGPETNSAAKLRVVV 336
            |.|:.:.|:...:.:   |....|....|...||.:||...::::||||..|   ..|..|.:..
  Fly    27 ISRVVNGTDSSVLKY---PFVVSLRSYDGSHSCGGSIISKHFVMTAAHCTNG---RPADTLSIQF 85

  Fly   337 GEHDLASSFETFATQRYDLDALILHEDFSQASGQPKNDIAMLKTRMAIVW-SQHVGPACLP---- 396
            |    .::..........:..:|.|||| ..:.|..|||::|.......: ...|.|..||
  Fly    86 G----VTNISAMGPNVVGIKKIIQHEDF-DPTRQNANDISLLMVEEPFEFDGVSVAPVELPALAF 145

  Fly   397 LQPGEDGQKLPLAGHQVVAAGWGTTSYGGPQTHRLLKATLDVIDGRRCRQALSSAGGL--PPHTF 459
            ..|..|      ||.:.|..|||.....|.....|.:.:|.:.....|   .|...|.  |.:..
  Fly   146 AVPQSD------AGVEGVLIGWGLNDTYGSVQDTLQEVSLKIYSDEEC---TSRHNGQTDPKYHI 201

  Fly   460 C--TYTPGRDTCQYDSGGALYERINGRLMAVGIVSFG-QAC-AAQQPSVNTRVASFIKWIRT 517
            |  ....|:..|..||||.|.  .||:  .|||||:. :.| .|..|.|..:|:.::.||::
  Fly   202 CGGVDEGGKGQCSGDSGGPLI--YNGQ--QVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKS 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14760	NP_610366.1	CUB	37..126	CDD:294042
		Tryp_SPc	281..516	CDD:238113	65/245 (27%)
		Tryp_SPc	281..515	CDD:214473	64/244 (26%)
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	66/251 (26%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	67/254 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456015
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930