DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14760 and CG32260

DIOPT Version :9

Sequence 1:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	93/354 - (26%)
Similarity:	138/354 - (38%)	Gaps:	93/354 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 RSSSKTSAKRARIVSSYPTAAP------SPGHGGGRFSCLVEAFQPTCSCGWSRIPRIASPTNEE 282
            ||.:..|.|...:.    ||||      ||..||...:.:|  ||||     ..:.::.||:
  Fly   248 RSGNARSRKDVFVT----TAAPFGFFHFSPLSGGSTATPMV--FQPT-----PPLSQVVSPS--- 298

  Fly   283 AVLHEFPP-------------------------MAGVLTKKHG-------------------KVF 303
                .:||                         :.|.:..:.|                   |..
  Fly   299 ----FYPPPPPPPPNNAPRESATCGISGATSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFL 359

  Fly   304 CGAAIIHHRYLLSAAHCFLGPETNSAAKLRVVVGEHDLASSFETFATQRYDLDALILHEDFSQAS 368
            ||.::||.||::::|||.     |....| |.:|.|||:...|:.|.. ..:...::||.|...|
  Fly   360 CGGSLIHSRYVITSAHCI-----NPMLTL-VRLGAHDLSQPAESGAMD-LRIRRTVVHEHFDLNS 417

  Fly   369 GQPKNDIAMLKTRMAIVWSQHVGPACLPLQPGEDGQKL---PLAGHQVVAAGWGTTSYGGPQTHR 430
              ..||||:::..:......::.|.|||     :..|.   ...|.....||||...:.|..:..
  Fly   418 --ISNDIALIELNVVGALPGNISPICLP-----EAAKFMQQDFVGMNPFVAGWGAVKHQGVTSQV 475

  Fly   431 LLKATLDVIDGRRCRQALSSA---GGLPPHTFCTYTPGRDTCQYDSGGAL-YERING---RLMAV 488
            |..|.:.::....|.|:..|.   ........|..:...|.||.||||.| ..::.|   |...:
  Fly   476 LRDAQVPIVSRHSCEQSYKSIFQFVQFSDKVLCAGSSSVDACQGDSGGPLMMPQLEGNVYRFYLL 540

  Fly   489 GIVSFGQACAAQQ-PSVNTRVASFIKWIR 516
            |:||||..||... |.|.|||||::.||:
  Fly   541 GLVSFGYECARPNFPGVYTRVASYVPWIK 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14760	NP_610366.1	CUB	37..126	CDD:294042
		Tryp_SPc	281..516	CDD:238113	73/289 (25%)
		Tryp_SPc	281..515	CDD:214473	72/288 (25%)
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	70/254 (28%)
		Tryp_SPc	328..571	CDD:238113	72/256 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456028
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940