DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14760 and C1r

DIOPT Version :9

Sequence 1:NP_610366.1 Gene:CG14760 / 35802 FlyBaseID:FBgn0033277 Length:529 Species:Drosophila melanogaster
Sequence 2:NP_001128027.1 Gene:C1r / 312705 RGDID:1309091 Length:707 Species:Rattus norvegicus


Alignment Length:555 Identity:116/555 - (20%)
Similarity:200/555 - (36%) Gaps:134/555 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 INSPYYPALYPVGTSCRYAVEAPKDHVLQFKCELQLRTLSTD----LKCRTEVFHFNSEGDEVLT 97
            |:|..||..||....|.|::...:...:..|.   |.....|    :.|..:.....:.|..:  
  Rat   205 ISSLEYPKPYPPDLRCNYSIRVERGLTVHLKF---LDPFEIDDHQQVHCPYDQLQIYANGKNL-- 264

  Fly    98 SSEYFCGSGKFERKSFLNRAVISYISSGHSEPPSAVKLKDKLHAVPTTSTTTEAPQAVSIEE--- 159
              ..|||:.:.......:.||.....:..|......||:       .|:...:.||..:::|   
  Rat   265 --GEFCGTQRPPDLDTSSNAVDLLFFTDESGDSRGWKLR-------YTTEIIKCPQPKALDEFTI 320

  Fly   160 -QDAEEEQEEEE----------EPEEADEDL--------SDEVLH------VLQDVGVSDALA-- 197
             ||.:.:.:..:          :..|..:.|        .|...|      .::|.|...:|:  
  Rat   321 IQDPQPQYQFRDYFIVTCKQGYQLMEGSQALLSFTAVCQHDGTWHRAMPRCKIKDCGQPRSLSNG 385

  Fly   198 ---YVASLLYDVEESRKSSTTIYLD----KLPIRSSSKTSAKRARIVSSYPTAAPSPGHGGGRFS 255
               |:.:...:..|:|   ...|..    |:..|:.|..|.:                   |.::
  Rat   386 DFRYLTTRGVNTYEAR---IQYYCHDPYYKMMTRAGSSESVR-------------------GIYT 428

  Fly   256 CLVEAF---------QPTCSCGWSRIPRIASPTN-----------EEAVLHEFPPMAGVLTKKHG 300
            |..:..         .|.|      :|....|.|           ::|....||..|  .|..||
  Rat   429 CTPQGIWKNEEEGEKMPRC------LPVCGKPVNPVTQKQRIIGGQKANPGNFPWQA--FTNIHG 485

  Fly   301 KVFCGAAIIHHRYLLSAAHCFLGPETNSAAKLR----VVVGEHDLASSFETFATQRYDLDALILH 361
            :  .|.|::..|::|:|||.....|.|....:.    |.:|..::.   |......:.:..:|:|
  Rat   486 R--GGGALLGDRWILTAAHTIYPKEHNKENNVNVSKDVFLGHTNVE---EIKKLGHHPVRRVIIH 545

  Fly   362 EDFSQASGQPKN---DIAMLKTRMAIVWSQHVGPACLPLQPGEDGQKLPLAGHQVVAAGWGTTSY 423
            .|:.|  .:|.|   |||:|:...::....::.|.|||  ..|......|.|:   .:|:|.|. 
  Rat   546 PDYRQ--DEPNNFEGDIALLELENSVTLGPNLLPICLP--DNETFYDKDLMGY---VSGFGITE- 602

  Fly   424 GGPQTHRLLKATLDVIDGRRCRQAL---SSAGGLPPHTFCTYTP--GRDTCQYDSGG--ALYERI 481
             ......|....|.:.|...|::.|   :|......:.||:..|  ..|.||.||||  |:.:|.
  Rat   603 -DKIAFNLRFVRLPIADREACQRWLRTKNSNDVFSQNMFCSGDPTLKHDACQGDSGGVFAVRDRS 666

  Fly   482 NGRLMAVGIVSFGQACAAQQPSVNTRVASFIKWIR 516
            ....:|.||||:|..| .:.....|::.:::.||:
  Rat   667 RDIWVATGIVSWGIGC-GEGYGFYTKLLNYVDWIK 700

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14760NP_610366.1 CUB 37..126 CDD:294042 18/92 (20%)
Tryp_SPc 281..516 CDD:238113 66/248 (27%)
Tryp_SPc 281..515 CDD:214473 65/247 (26%)
C1rNP_001128027.1 CUB 27..138 CDD:214483
FXa_inhibition 161..189 CDD:291342
CUB 195..302 CDD:278839 21/110 (19%)
Sushi 309..371 CDD:278512 9/61 (15%)
Sushi 376..447 CDD:278512 13/92 (14%)
Tryp_SPc 463..699 CDD:214473 65/252 (26%)
Tryp_SPc 464..701 CDD:238113 67/254 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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