DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14760 and Corin

DIOPT Version :9

Sequence 1:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_872279.2	Gene:	Corin / 289596	RGDID:	727887	Length:	1111	Species:	Rattus norvegicus

Alignment Length:	238	Identity:	62/238 - (26%)
Similarity:	102/238 - (42%)	Gaps:	30/238 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 FPPMAGVLTKKHGKVFCGAAIIHHRYLLSAAHCFLGPETNSAAKLRVVVGEHDLASSFETFATQR 352
            :|....:.::..|.: ||..:|..:::|:.||||.|.|.....|:...:...|..|.|    .|.
  Rat   878 WPWQCSLQSEPSGHI-CGCVLIAKKWVLTVAHCFEGREDADVWKVVFGINNLDHPSGF----MQT 937

  Fly   353 YDLDALILHEDFSQASGQPKNDIAMLKTRMAIVWSQHVGPACLP-----LQPGEDGQKLPLAGHQ 412
            ..:..::||..:|:|  ....||::::....|..:.:|.|.|||     |:|..          .
  Rat   938 RFVKTILLHPRYSRA--VVDYDISVVELSDDINETSYVRPVCLPSPREFLEPDT----------Y 990

  Fly   413 VVAAGWGTTSYGGPQTHRLLKATLDVIDGRRCRQALSSAGGLPPHTFCT-YTPGR-DTCQYDSGG 475
            ....|||  ..|.....:|.:..:.:|...:| |:......:.....|. |..|. |:|..||||
  Rat   991 CYITGWG--HMGNKMPFKLQEGEVRIIPLEQC-QSYFDMKTITNRMICAGYESGTVDSCMGDSGG 1052

  Fly   476 ALY-ERINGRLMAVGIVSFGQACAAQ--QPSVNTRVASFIKWI 515
            .|. ||..|:....|:.|:|..|.::  .|.|.:.|:.|:.||
  Rat  1053 PLVCERPGGQWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVDWI 1095

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14760	NP_610366.1	CUB	37..126	CDD:294042
		Tryp_SPc	281..516	CDD:238113	62/238 (26%)
		Tryp_SPc	281..515	CDD:214473	60/236 (25%)
Corin	NP_872279.2	DDNN motif	93..96
		CRD_corin_1	200..329	CDD:143554
		LDLa	335..370	CDD:238060
		LDLa	372..406	CDD:238060
		Ldl_recept_a	413..443	CDD:395011
		LDLa	453..480	CDD:238060
		CRD_corin_2	521..641	CDD:143579
		Ldl_recept_a	646..680	CDD:395011
		LDLa	<693..718	CDD:238060
		LDLa	721..755	CDD:238060
		SRCR_2	779..859	CDD:413346
		Tryp_SPc	867..1098	CDD:238113	62/238 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000