DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14760 and F9

DIOPT Version :9

Sequence 1:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_113728.1	Gene:	F9 / 24946	RGDID:	2589	Length:	462	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	67/256 - (26%)
Similarity:	123/256 - (48%)	Gaps:	27/256 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 TNEEAVLHEFPPMAGVLTKKHGKV------------FCGAAIIHHRYLLSAAHCFLGPETNSAAK 331
            |.....:::|..:.|....|.|::            |||.|||:.:::::|||| |.|    ..|
  Rat   216 TENSEPINDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHC-LKP----GDK 275

  Fly   332 LRVVVGEHDLASSFETFATQRYDLDALILHEDFSQASGQPKNDIAMLKTRMAIVWSQHVGPACLP 396
            :.||.|||::....:|  .||.::...|.|..::....:..:|||:|:....::.:.:|.|.|:
  Rat   276 IEVVAGEHNIDEKEDT--EQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICV- 337

  Fly   397 LQPGEDGQKLPLAGHQVVAAGWGTTSYGGPQTHRLLKATLDVIDGRRCRQALSSAGGLPPHTFCT 461
              ..::...:.|.......:|||.....|.|...|....:.::|...|.:  |:...:..:.||.
  Rat   338 --ANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLR--STKFSIYNNMFCA 398

  Fly   462 -YTP-GRDTCQYDSGGALYERINGRLMAVGIVSFGQACAAQ-QPSVNTRVASFIKWIRTKS 519
             |.. |:|:|:.||||.....:.|.....||:|:|:.||.: :..:.|:|:.::.||:.|:
  Rat   399 GYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKT 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14760	NP_610366.1	CUB	37..126	CDD:294042
		Tryp_SPc	281..516	CDD:238113	64/249 (26%)
		Tryp_SPc	281..515	CDD:214473	63/248 (25%)
F9	NP_113728.1	GLA	21..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	127..163	CDD:291342
		Tryp_SPc	227..455	CDD:214473	62/239 (26%)
		Tryp_SPc	228..458	CDD:238113	64/241 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000