Protein Alignment pnut and Septin7

DIOPT Version :10

• Sequence 1: NP_477064.1
• Gene: pnut / 35801
• FlyBaseID: FBgn0013726
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001107212.1
• Gene: Septin7 / 64551
• RGDID: 620469
• Length: 437
• Species: Rattus norvegicus
• Alignment Length: 430
• Identity: 277/430 - (64%)
• Similarity: 336/430 - (78%)
• Gaps: 20/430 - (4%)

  Fly   115 KPMEIAGYVGFANLPNQVYRKAVKRGFEFTLMVVGASGLGKSTLINSMFLSDIYNAEQYPGPSLR 179
            :|..:.|||||||||||||||:|||||||||||||.|||||||||||:||:|:|:.| |||||.|
  Rat    23 QPKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPE-YPGPSHR 86

  Fly   180 KKKTVAVEATKVMLKENGVNLTLTVVDTPGFGDAVDNSNCWVPILEYVDSKYEEYLTAESRVYRK 244
            .||||.||.:||::||.||.|.||:||||||||||||||||.|:::|:|||:|:||.|||||.|:
  Rat    87 IKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRR 151

  Fly   245 TISDSRVHCCLYFIAPSGHGLLPLDIACMQSLSDKVNLVPVIAKADTMTPDEVHLFKKQILNEIA 309
            .:.|:||.|||||||||||||.||||..|:.|.:|||::|:||||||:||:|...|||||:.||.
  Rat   152 QMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQ 216

  Fly   310 QHKIKIYDFPATLEDAAEEAKTTQNLRSRVPFAVVGANTIIEQDGKKVRGRRYPWGLVEVENLTH 374
            :||||||:||.|  |..||.|..:.::.|:|.||||:|||||.:||:||||:||||:.||||..|
  Rat   217 EHKIKIYEFPET--DDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEH 279

  Fly   375 CDFIALRNMVIRTHLQDLKDVTNNVHYENYRCRKLSELGL--VD---GKARLSNKNPLTQMEEEK 434
            |||..||||:||||:||||||||||||||||.|||:.:..  ||   .|.:|: |:||.|||||:
  Rat   280 CDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLT-KSPLAQMEEER 343

  Fly   435 REHEQKMKKMEAEMEQVFDMKVKEKMQKLRDSELELARRHEERKKALELQIRELEEKRREFEREK 499
            |||..||||||.||||||:||||||:|||:|||.||.||||:.||.||.|.:|||||||:||.||
  Rat   344 REHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEEEK 408

  Fly   500 KEWEDVNHVTLEELKRRSLGANSSTDNVDGKKEKKKKGLF 539
            ..||....:..::...|:|           :|.|||..:|
  Rat   409 ANWEAQQRILEQQNSSRTL-----------EKNKKKGKIF 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pnut	NP_477064.1	3a0901s04IAP86	58..>210	CDD:273381	70/94 (74%)
		Septin	140..411	CDD:395596	188/270 (70%)
		UDM1_RNF168	427..484	CDD:409018	43/56 (77%)
Septin7	NP_001107212.1	CDC_Septin	47..317	CDD:206649	189/272 (69%)
		Interaction with SEPTIN12. /evidence=ECO:0000250|UniProtKB:Q16181	47..317		189/272 (69%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	57..64		5/6 (83%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	113..116		2/2 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	194..197		2/2 (100%)
		PRK12704	337..>433	CDD:237177	60/106 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..437		30/69 (43%)