Protein Alignment pnut and SEPTIN3

DIOPT Version :9

• Sequence 1: NP_477064.1
• Gene: pnut / 35801
• FlyBaseID: FBgn0013726
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001350774.1
• Gene: SEPTIN3 / 55964
• HGNCID: 10750
• Length: 856
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 185/492 - (37%)
• Similarity: 265/492 - (53%)
• Gaps: 93/492 - (18%)

  Fly     1 MNSPRSNAVNGGSGGAISALPSTLAQLALRDKQQAASASA-------SSATNGSSGSESLVG--V 56
            |:|..|:.|.          |.|:.......:.:.|.|.|       .:|.|..:...|.:|  |
Human   381 MDSATSDPVK----------PDTITATVGTSRLETAMALARVNRAKLGTAKNSLALDTSRMGTAV 435

  Fly    57 GGRPPNQPPSVPVAASGKLDTSGGGASN-------------GDSNKLTHDLQEKEHQQAQKP--- 105
            |    :..|..|..|:||  |:.|..:|             ..|..|..|.......:|.:|
Human   436 G----SVVPVTPDPATGK--TTLGSVNNLTISDVATCLLMPSRSTDLALDNTNAAMDRATEPASL 494

  Fly   106 --------------------------QKPPLPVRQKPMEI----AGYVGFANLPNQVYRKAVKRG 140
                                      .||.:|:  |||.|    .||:|...:..|:.:|.:|.|
Human   495 DLATEYKGLPETRTDAAMSELVPEPRPKPAVPM--KPMSINSNLLGYIGIDTIIEQMRKKTMKTG 557

  Fly   141 FEFTLMVVGASGLGKSTLINSMFLSDI------YNAEQYPGPSLRKKKTVAVEATKVMLKENGVN 199
            |:|.:||||.||||||||:|::|.|.:      :|.|:      :..|||.::|...:::|.||.
Human   558 FDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREE------KIPKTVEIKAIGHVIEEGGVK 616

  Fly   200 LTLTVVDTPGFGDAVDNSNCWVPILEYVDSKYEEYLTAESRVYR-KTISDSRVHCCLYFIAPSGH 263
            :.|||:|||||||.::|.|||.||.:|::.:||::|..|..:.| |.|.|:|||||||||:|:||
Human   617 MKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGH 681

  Fly   264 GLLPLDIACMQSLSDKVNLVPVIAKADTMTPDEVHLFKKQILNEIAQHKIKIY---DFPATLEDA 325
            .|.|||:..|:.||..||::||||||||||.:|...||:::..|:..:.|:.|   :|...|||.
Human   682 SLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDK 746

  Fly   326 AEEAKTTQNLRSRVPFAVVGANTIIEQDGKKVRGRRYPWGLVEVENLTHCDFIALRNMVIRTHLQ 390
            .|..|..|   ..:||||||::...:.:||:|.||:.|||::|||||.||:|..||:.|||||||
Human   747 TENDKIRQ---ESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQ 808

  Fly   391 DLKDVTNNVHYENYRCRKLSEL-GLVDGKARLSNKNP 426
            |||:||:|:|||.||.::|::. ||..|:..|....|
Human   809 DLKEVTHNIHYETYRAKRLNDNGGLPPGEGLLGTVLP 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pnut	NP_477064.1	CDC3	121..482	CDD:227352	150/317 (47%)
		Septin	139..411	CDD:279124	139/281 (49%)
SEPTIN3	NP_001350774.1	CDC_Septin	557..831	CDD:206649	139/282 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D452703at33208
OrthoFinder	1	1.000	-	-		FOG0000103
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850